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24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis

NCT04303390 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 568

Last updated 2023-04-11

No results posted yet for this study

Summary

A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin (Cefuroxime).

Conditions

  • Surgical Site Infection

Interventions

DRUG

Cefuroxime

second generation cephalosporin

DRUG

Cefazolin

First generation cephalosporin

OTHER

24 hours

Duration of antibiotic therapy

OTHER

48 hours

Duration of antibiotic therapy

Sponsors & Collaborators

  • Saud Al Babtain Cardiac Center

    lead OTHER_GOV

Principal Investigators

  • Mohammed S Koudieh, MD · Saud AlBabtain Cardiac Center

  • Shukri M AlSaif, MD · Saud AlBabtain Cardiac Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-06
Primary Completion
2022-05-31
Completion
2022-05-31

Countries

  • Saudi Arabia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04303390 on ClinicalTrials.gov