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Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma

NCT04302610 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2020-03-10

No results posted yet for this study

Summary

The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments. We will investigate the potential protective benefits of the face masks against exercise induced asthma during 1) a "one-off" bout of exercise in a cold dry environment and 2) over the course of a four week period, exercising three times per week in a cold dry environment.

Conditions

  • Asthma, Exercise-Induced
  • Asthma

Interventions

DEVICE

Heat and Moisture Exchange mask (ColdAvenger® expedition balaclava, USA,

A heat and moisture exchange mask will warm and humidify inspired air and therefore reduce airway heat and water loss during exercise. This will potentially reduce the incidence of and severity of EIB and may also have the potential to decrease the incidence of cough amongst athletes engaging in sports in cold dry environments

DEVICE

Sham treatment

Same as the HME mask but active HME parts withdrawn from devices and multiple holes made in mouth piece to improve ventilation of mask and reduce HME ability of mask

Sponsors & Collaborators

  • Asthma UK

    collaborator OTHER

  • Royal Brompton & Harefield NHS Foundation Trust

    collaborator OTHER

  • King's College Hospital NHS Trust

    collaborator OTHER

  • University of Kent

    lead OTHER

Principal Investigators

  • John W Dickinson, PhD · University of Kent

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-01
Primary Completion
2018-04-01
Completion
2018-05-15

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04302610 on ClinicalTrials.gov