A Study to Assess the Safety and Efficacy of Lenvatinib as First-line Treatment in Participants With Unresectable HCC
NCT04297254 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2023-11-15
Summary
The primary objective of this study is to evaluate the safety of lenvatinib in HCC.
Conditions
- Carcinoma, Hepatocellular
Interventions
- DRUG
-
Lenvatinib capsules.
Sponsors & Collaborators
-
Eisai Pharmaceuticals India Pvt. Ltd
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-02-04
- Primary Completion
- 2023-07-31
- Completion
- 2023-07-31
Countries
- India
Study Locations
More Related Trials
-
Trial to Evaluate Safety and Efficacy of Treatment of Physician Choice (TPC) Following First-Line Treatment of Lenvatinib in Subjects With Unresectable Hepatocellular Carcinoma (uHCC)
NCT03433703 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Lenvatinib (E7080) in Participants With Advanced Hepatocellular Carcinoma (HCC)
NCT00946153 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Lenvatinib After Progression on Atezolizumab-bevacizumab in Hepatocellular Carcinoma
NCT06138769 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
First-Line Lenvatinib in Child-Pugh B Patients With HCC Unsuitable for Curative Treatment
NCT07297654 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Lenvatinib Combined With Gefitinib in the Treatment of Lenvatinib-resistant Hepatocellular Carcinoma
NCT04642547 ·Status: COMPLETED ·Phase: NA
-
Real-world Study of Lenalidomide After First-line Treatment Lenvatinib With PD-1 in Advanced HCC
NCT07184424 ·Status: COMPLETED ·Phase: NA
-
Lenvatinib Plus Tislelizumab With or Without TACE in First-line Treatment of Unresectable HCC
NCT05842317 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Safety and Efficacy Study of Lenvatinib Combined With VIC-1911 for the Treatment of Advanced HCC
NCT06519721 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Lenvatinib Plus I-125 Seed Brachytherapy vs. Lenvatinib for TACE-refractory HCC
NCT05608213 ·Status: RECRUITING ·Phase: PHASE3
-
Preliminary Antitumor Activity, Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma
NCT04401800 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Lenvatinib in Subjects With HCC Progression After First Line Treatment With Checkpoint Inhibitors
NCT04428437 ·Status: TERMINATED
-
To Study the Effects of Addition of Mebendazole to Lenvatinib in Cirrhotics With Advanced Hepatocellular Carcinoma.
NCT04443049 ·Status: UNKNOWN ·Phase: NA
-
Lenvatinib Following Liver Transplantation in Patients With High-Risk Hepatocellular Carcinoma
NCT04168944 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
A Study of Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma
NCT03418922 ·Status: COMPLETED ·Phase: PHASE1
-
Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant
NCT05103904 ·Status: TERMINATED ·Phase: PHASE2
-
Lenvatinib+Sintilimab+TACE vs. Lenvatinib+TACE for Advanced HCC
NCT05608200 ·Status: RECRUITING ·Phase: PHASE3
-
Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer
NCT04656249 ·Status: COMPLETED ·Phase: PHASE2
-
Lenalidomide as Second-line Treatment for Advanced Hepatocellular Carcinoma
NCT01545804 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Overall Survival in Participants With Unresectable Hepatocellular Carcinoma
NCT04008082 ·Status: COMPLETED
-
Lenvatinib in Combination With Camrelizumab as First-Line Therapy in Patients With Advanced HCC
NCT04443309 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Lenvatinib vs Bevacizumab Plus ICIs and HAIC in Unresectable HCC
NCT06435013 ·Status: COMPLETED
-
Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative
NCT05113186 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
TACE Combined With Lenvatinib for Unresectable Hepatocellular Carcinoma (Prolong)
NCT04560751 ·Status: UNKNOWN
-
Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma
NCT05444478 ·Status: RECRUITING ·Phase: NA
-
Durvalumab Plus Lenvatinib as First-line Treatment for Unresectable Hepatocellular Carcinoma
NCT05312216 ·Status: UNKNOWN ·Phase: PHASE2