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Economic Evaluation of Vancomycin Therapeutic Drug Monitoring Methods

NCT04297176 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 65

Last updated 2022-08-15

No results posted yet for this study

Summary

Vancomycin is a widely used antibiotic in the treatment of complicated gram positive infections. Approaches to vancomycin therapeutic drug monitioring (TDM) vary. This clinical trial aimed to compare the pharmacoeconomic outcomes between various vancomyicn TDM approaches.

Research questions: Which vancomycin therapeutic drug monitoring (TDM) approach is associated with superior economic outcomes?

-Objectives: In this proposed multicenter randomized controlled trial (RCT), we aim to compare the pharmacoeconomic outcomes of various vancomycin TDM approaches.

Conditions

  • Infection, Bacterial

Interventions

DRUG

Vancomycin-traditional dosing

The dose is calculated based on 2 vancomycin serum levels

DRUG

Vancomycin- Trough-only based dosing

The dose is calculated based on 1 vancomycin serum level (i.e. trough)

Sponsors & Collaborators

  • Qatar University

    collaborator OTHER

  • Hamad Medical Corporation

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-23
Primary Completion
2021-05-04
Completion
2021-07-02

Countries

  • Qatar

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04297176 on ClinicalTrials.gov