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Impact of Severe Intraoperative Hyperglycemia on Infection Rate After Elective Intracranial Interventions

NCT04285359 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 514

Last updated 2021-04-30

No results posted yet for this study

Summary

Severe intraoperative hyperglycemia (SIH) is recognized as one of the important risk factors for the increasing of the postoperative infections rate, which can negatively affect the final outcome of surgical treatment. Studies in recent years have shown a much higher incidence of wound infections, respiratory and urinary tract infections in patients who intraoperatively had an increase in blood glucose level (BGL) above 180 mg/dl (10 mmol/l). This problem in neurosurgery is especially important due to the high proportion of patients with acute injuries and potentially long-term need for postoperative intensive care, as well as the frequent use of drugs that increase blood glucose level (steroids) in neurooncology. Most published studies include patients from both of these groups. This study is aimed to assess the impact of severe intraoperative hyperglycemia on the incidence of infectious complications only in patients scheduled for elective intracranial interventions.

Conditions

Interventions

PROCEDURE

Intracranial Interventions

Neurosurgical elective intracranial interventions: supra- and infratentorial craniotomies, transnasal endoscopic interventions.

Sponsors & Collaborators

  • Burdenko Neurosurgery Institute

    lead OTHER

Principal Investigators

  • Alexander Kulikov · Burdenko National Medical Research Center of Neurosurgery

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-28
Primary Completion
2021-03-15
Completion
2021-04-01

Countries

  • Italy
  • Russia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04285359 on ClinicalTrials.gov