Trial Outcomes & Findings for Families, Children and Teachers Thriving Together (NCT NCT04276363)

NCT ID: NCT04276363

Last Updated: 2026-05-07

Results Overview

Parents report on Attention Problems on the PSC. Tis 5-item subscale screens psychosocial functioning in children 4-18 years of age. Parents are asked to rate the frequency of each symptom on a three-point scale ranging from "Never" (0) to "Often" (2). Scores are summed and range from 0-10, with higher scores indicating high attention problems.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

458 participants

Primary outcome timeframe

End of Kindergarten, on average 22 months

Results posted on

2026-05-07

Participant Flow

Parents of pre-K students were invited to participate in the study in Fall 2019. The parent of the pre-K student provided consent for participation for both their pre-K child and themselves, only the parents provided consent. 81 district schools with Pre-K programs were selected for the study in late Spring 2017 by the NYC DOE. 20 schools were randomized to Thrive Professional Learning plus ParentCorps, 21 schools to Thrive Professional Learning only, 40 schools to Inspire Professional Learning.

The Protocol Enrollment, Number Started and Completed reflected dyads.

Unit of analysis: Schools

Participant milestones

Participant milestones
Measure
Thrive Professional Learning Plus ParentCorps
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Thrive Professional Learning Only
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Overall Study
STARTED
121 20
120 21
217 40
Overall Study
COMPLETED
81 20
85 21
156 40
Overall Study
NOT COMPLETED
40 0
35 0
61 0

Reasons for withdrawal

Reasons for withdrawal
Measure
Thrive Professional Learning Plus ParentCorps
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Thrive Professional Learning Only
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Overall Study
Lost to Follow-up
40
35
61

Baseline Characteristics

Families, Children and Teachers Thriving Together

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Thrive Professional Learning Plus ParentCorps
n=81 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Thrive Professional Learning Only
n=85 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=156 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Total
n=322 Participants
Total of all reporting groups
Age, Continuous
4.57 years
STANDARD_DEVIATION 0.3 • n=54 Participants
4.44 years
STANDARD_DEVIATION 0.3 • n=60 Participants
4.46 years
STANDARD_DEVIATION 0.31 • n=114 Participants
4.48 years
STANDARD_DEVIATION 0.31 • n=318 Participants
Sex: Female, Male
Female
40 Participants
n=54 Participants
45 Participants
n=60 Participants
93 Participants
n=114 Participants
178 Participants
n=318 Participants
Sex: Female, Male
Male
41 Participants
n=54 Participants
40 Participants
n=60 Participants
63 Participants
n=114 Participants
144 Participants
n=318 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
45 Participants
n=54 Participants
63 Participants
n=60 Participants
98 Participants
n=114 Participants
206 Participants
n=318 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
36 Participants
n=54 Participants
21 Participants
n=60 Participants
51 Participants
n=114 Participants
108 Participants
n=318 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=54 Participants
1 Participants
n=60 Participants
7 Participants
n=114 Participants
8 Participants
n=318 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=54 Participants
0 Participants
n=60 Participants
0 Participants
n=114 Participants
1 Participants
n=318 Participants
Race (NIH/OMB)
Asian
4 Participants
n=54 Participants
3 Participants
n=60 Participants
3 Participants
n=114 Participants
10 Participants
n=318 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=54 Participants
0 Participants
n=60 Participants
0 Participants
n=114 Participants
0 Participants
n=318 Participants
Race (NIH/OMB)
Black or African American
25 Participants
n=54 Participants
17 Participants
n=60 Participants
38 Participants
n=114 Participants
80 Participants
n=318 Participants
Race (NIH/OMB)
White
5 Participants
n=54 Participants
1 Participants
n=60 Participants
9 Participants
n=114 Participants
15 Participants
n=318 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=54 Participants
0 Participants
n=60 Participants
1 Participants
n=114 Participants
2 Participants
n=318 Participants
Race (NIH/OMB)
Unknown or Not Reported
45 Participants
n=54 Participants
64 Participants
n=60 Participants
105 Participants
n=114 Participants
214 Participants
n=318 Participants
Region of Enrollment
United States
81 participants
n=54 Participants
85 participants
n=60 Participants
156 participants
n=114 Participants
322 participants
n=318 Participants

PRIMARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning (PL) plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 42 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 75 did not complete the measure at the end of Kindergarten.

Parents report on the Anger subscale from the NIH Toolbox Emotion Battery. This measure was designed for children ages 3 - 7. The Anger subscale includes 9 items which measure attitudes of hostility and cynicism often associated with experiences of frustration impeding goal-directed behavior. Parents are asked to respond to items on a three-point scale ranging from "Never True" to "Often True". The NIH Toolbox uses a T-score metric where a score of 50 is the mean and 10 is the standard deviation. A higher T-score indicates higher anger.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=49 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=81 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
NIH Toolbox Emotion Battery Test Anger Subscale Score
56.44 T-score
Standard Deviation 9.11
52.19 T-score
Standard Deviation 10.77
49.8 T-score
Standard Deviation 11.13

PRIMARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 36 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 76 did not complete the measure at the end of Kindergarten.

Parents report on Attention Problems on the PSC. Tis 5-item subscale screens psychosocial functioning in children 4-18 years of age. Parents are asked to rate the frequency of each symptom on a three-point scale ranging from "Never" (0) to "Often" (2). Scores are summed and range from 0-10, with higher scores indicating high attention problems.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=49 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=80 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Pediatric Symptom Checklist (PSC) Score
4.65 units on a scale
Standard Deviation 2.51
3.71 units on a scale
Standard Deviation 2.41
3.52 units on a scale
Standard Deviation 2.23

PRIMARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 36 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 76 did not complete the measure at the end of Kindergarten.

Parents report on two subscales, Prosocial/Communication Skills and Emotional Regulation Skills, on the Social Competence Scale. This 12-item measure assesses a child's prosocial behaviors, communication skills, and self-control. Parents respond to items on a five-point scale ranging from "Not at All" to "Very well". Scores are summed on both subscales for a total scale score, scores range from 0 to 48. Higher scores reflect higher parent-reported social competence.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=49 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=80 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Social Competence Scale - Parent Version Score
2.44 units on a scale
Standard Deviation 0.84
2.54 units on a scale
Standard Deviation 0.69
2.72 units on a scale
Standard Deviation 0.85

PRIMARY outcome

Timeframe: End of Pre-Kindergarten, on average 9 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 23 did not complete the measure at the end of pre-Kindergarten. Out of the 85 participants in the Thrive PL, 30 did not complete this measure at the end of pre-Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 52 did not complete the measure at the end of pre-Kindergarten.

Parents report on the Foundational Education sub-scale of the Parental Engagement of Families Questionnaire (PEFL). This measure captures parental engagement designed for and validated with Latino Head Start families. The 20-item Foundational Education sub-scale reflects parents' efforts to teach their children "the basics". Parents respond to each item using a 4-point rating scale ranging from 1 (Never) to 4 (Frequently). Raw summed scores are converted to T-scores where a score of 50 is the mean and 10 is the standard deviation. Higher scores indicates higher parent-reported social competence.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=55 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=104 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=58 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
The Parental Engagement of Families Questionnaire (PEFL) Score
50.15 T-score
Standard Deviation 7.89
50.9 T-score
Standard Deviation 8.3
51.82 T-score
Standard Deviation 7.17

SECONDARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 42 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 75 did not complete the measure at the end of Kindergarten.

Parents report on three sub-scales from the NIH Toolbox Emotion Battery. This measure was designed for children ages 3 - 7. The Fear-Over Anxious subscale includes 6 items measuring symptoms of anxiety that reflect autonomic arousal and perceptions of threat. The Fear-Separation Anxiety subscale includes 7 items measuring symptoms of anxiety that reflect autonomic arousal and perceptions of threat. The Sadness subscale includes 7 items measuring low levels of positive affect. Parents are asked to respond to items on a three-point scale ranging from "Never True" to "Often True". All subscales are summed for a total score. The NIH Toolbox uses a T-score metric where a score of 50 is the mean and 10 is the standard deviation. The average of the three sub-scales is calculated. A higher T-score indicates higher anxiety, separation anxiety and sadness.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=43 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=81 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
NIH Toolbox Emotion Battery Test Score
55.88 T-score
Standard Deviation 8.98
53.29 T-score
Standard Deviation 9.89
50.85 T-score
Standard Deviation 8.92

SECONDARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 36 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 75 did not complete the measure at the end of Kindergarten.

Parents report on the Patient-Reported Outcomes Measurement Information System (PROMIS) -4 sleep disturbance questionnaire. This 4-item questionnaire assesses child's sleep disturbances. Parents report on a 5-point scale ranging from "Never" to "Always". Scores are converted to a T-score, where a score of 50 is the mean and 10 is the standard deviation. Higher T-scores reflect high sleep disturbance.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=49 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=81 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
PROMIS-4 Sleep Disturbance Questionnaire Score
48.67 T-score
Standard Deviation 9.37
47.06 T-score
Standard Deviation 8.2
45.9 T-score
Standard Deviation 9.4

SECONDARY outcome

Timeframe: End of Pre-Kindergarten, on average 9 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 24 did not complete the measure at the end of pre-Kindergarten. Out of the 85 participants in the Thrive PL, 33 did not complete this measure at the end of pre-Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 55 did not complete the measure at the end of pre-Kindergarten.

Parents report on the Parent Evidence-Based Strategies Scale, which is adapted from the Parent Practices Interview (PPI). This 6-item scale assesses the frequency in which parents apply a range of evidence-based parenting strategies (e.g., behavioral management, promotion strategies). Parents report on a 5-point scale, ranging from 1 (Never) to 5 (Very Often). Items are scored for a total score, scores range from 6-30. Higher scores reflect higher frequency of evidence-based strategies in parenting.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=52 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=101 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=57 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Parent Evidence-Based Strategies Scale
24.47 units on a scale
Standard Deviation 3.54
24.64 units on a scale
Standard Deviation 4.05
25.54 units on a scale
Standard Deviation 3.48

SECONDARY outcome

Timeframe: End of Kindergarten, on average 22 months

Population: Out of the 81 in the Thrive Professional Learning plus ParentCorps, 41 did not complete the measure at the end of Kindergarten. Out of the 85 participants in the Thrive PL, 36 did not complete this measure at the end of Kindergarten. Out of the 156 participants in the Inspire Professional Learning, 75 did not complete the measure at the end of Kindergarten.

Parents report on the Daily Living Routines subscale of the Child Routines Inventory (CRI). This measures commonly occurring routines in school-aged children. This 11-item subscale consists of routines around activities of daily living, such as morning routine and bedtime routine. Parents report on a 5-point scale, ranging from "Almost Never" to "Nearly Always". Scores are summed and range from 0-44, with high scores reflecting higher frequency of routines related to daily activities.

Outcome measures

Outcome measures
Measure
Thrive Professional Learning Only
n=49 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning only.
Inspire Professional Learning
n=81 Participants
Parents with a child enrolled at a participating school with teachers who received the inspire professional learning only.
Thrive Professional Learning Plus ParentCorps
n=40 Participants
Parents with a child enrolled at a participating school with teachers who received the thrive professional learning plus ParentCorps.
Daily Living Routines Subscale of the Child Routines Inventory (CRI) Score
3.41 units on a scale
Standard Deviation 0.65
3.33 units on a scale
Standard Deviation 0.61
3.4 units on a scale
Standard Deviation 0.76

Adverse Events

Thrive Professional Learning Plus ParentCorps

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Thrive Professional Learning Only

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Inspire Professional Learning

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Laurie Miller Brotman, Ph.D.

NYU Langone Health

Phone: 646-754-4999

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place