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Overweight and Obesity as Prognostic Factors for Survival in Children With Acute Lymphoblastic Leukemia

NCT04271215 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1200

Last updated 2022-07-20

No results posted yet for this study

Summary

Background: Mexico City has one of the highest incidences and mortality rates of acute lymphoblastic leukemia (ALL) in the world and a high frequency of early relapses (17%) and early mortality (15%). Otherwise, childhood overweight and obesity are reaching epidemic proportions. They have been associated with poor outcomes in children with ALL. The aim of present study is to identify if overweight and obesity are prognostic factors associated with survival rates in Mexican children with ALL. Methods: Multicenter cohort study. ALL children younger than 15 years old are included and followed-up. Overweight and obesity are classified according World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) criteria. Deaths and relapses are the main outcomes.

Conditions

  • Leukemia, Lymphoblastic

Interventions

OTHER

Chemotherapy protocol used

Chemotherapy protocol used in each participating hospital

Sponsors & Collaborators

  • Coordinación de Investigación en Salud, Mexico

    lead OTHER_GOV

Principal Investigators

  • Juan M Mejía-Arangure, PhD · Instituto Mexicano del Seguro Social/Instituto Nacional de Medicina Genomica

Eligibility

Min Age
1 Day
Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-01
Primary Completion
2021-12-31
Completion
2022-12-31

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04271215 on ClinicalTrials.gov