The Efficacy of Different Hormone Doses in 2019-nCoV Severe Pneumonia
NCT04263402 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2020-03-17
Summary
At present, there is no specific and effective antiviral therapy.In this study, an open, prospective/retrospective, randomized controlled cohort study was designed to compare the efficacy of different hormone doses in the treatment of 2019-nCoV severe Pneumonia.This study explores effective treatment programs for 2019-nCoV severe pneumonia and provides a reliable evidence-based basis for the treatment.
Conditions
- 2019-nCoV Severe Pneumonia
Interventions
- DRUG
-
Methylprednisolone
Patients in the Group I will receive basic symptomatic supportive treatment,plus methylprednisolone(\<40mg/d intravenous drip for 7 days).
- DRUG
-
Methylprednisolone
Patients in the Group II will receive basic symptomatic supportive treatment,plus methylprednisolone(40\~80mg/d intravenous drip for 7 days).
Sponsors & Collaborators
-
Tongji Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-02-01
- Primary Completion
- 2020-06-01
- Completion
- 2020-07-01
Countries
- China
Study Locations
More Related Trials
-
Efficacy and Safety of Corticosteroids in Oxygen-dependent Patients With COVID-19 Pneumonia
NCT04359511 ·Status: WITHDRAWN ·Phase: PHASE3
-
A Study to Evaluate the Efficacy and Safety of Pirfenidone With Novel Coronavirus Infection
NCT04282902 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison Between Prednisolone and Dexamethasone on Mortality in Patients on Oxygen Therapy, with CoViD-19
NCT04765371 ·Status: COMPLETED ·Phase: PHASE3
-
Corticosteroids During Covid-19 Viral Pneumonia Related to SARS-Cov-2 Infection
NCT04344288 ·Status: TERMINATED ·Phase: PHASE2
-
Early Short Course Corticosteroids in COVID-19
NCT04374071 ·Status: COMPLETED
-
The Efficacy of Intravenous Immunoglobulin Therapy for Severe 2019-nCoV Infected Pneumonia
NCT04261426 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
The Standard of Care Combined With Glucocorticoid in Elderly People With Mild or Moderate COVID-19
NCT05855395 ·Status: UNKNOWN ·Phase: NA
-
Effect of Treatments in Patients Hospitalized for Severe COVID-19 Pneumonia: a Multicenter Cohort Study
NCT04365764 ·Status: COMPLETED
-
Prophylactic Corticosteroid to Prevent COVID-19 Cytokine Storm
NCT04355247 ·Status: UNKNOWN ·Phase: PHASE2
-
Biomarkers for Dexamethasone Response in Sars-Cov-2 / COVID-19 Pneumonia
NCT04619693 ·Status: TERMINATED
-
Individualizing Corticosteroid Use in Pneumonia
NCT05334316 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia
NCT04409262 ·Status: COMPLETED ·Phase: PHASE3
-
Steroid and Anticoagulant Therapy in covid19
NCT05021588 ·Status: COMPLETED ·Phase: NA
-
Comparison of Two Corticosteroid Regimens for Post COVID-19 Diffuse Lung Disease
NCT04657484 ·Status: COMPLETED ·Phase: NA
-
Study for Novel Coronavirus Pneumonia (NCP)
NCT04283396 ·Status: UNKNOWN
-
Clinical Progressive Characteristics and Treatment Effects of 2019-novel Coronavirus
NCT04292327 ·Status: UNKNOWN
-
Extended Steroid in Use in Community Acquired Pneumonia (CAP)(e)
NCT01283009 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Clinical Parameters on Admission and Medications in Covid-19 Pneumonia (Corona Virus Disease 2019)
NCT04379310 ·Status: COMPLETED
-
Utility of Empiric Antibiotics for Non-intubated Novel Coronavirus Diseases 2019 Patients
NCT04674410 ·Status: WITHDRAWN
-
Evaluation of Corticosteroids Use and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Study
NCT05844410 ·Status: COMPLETED
-
Randomized, Controlled Study of IFX-1 in Patients With Severe COVID-19 Pneumonia
NCT04333420 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Randomized Adaptive Platform Trial of Pathogen-Directed Anti-inflammatory Therapy in Severe Community-Acquired Pneumonia(Core Protocal)
NCT07152587 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Oral Prednisone Regimens to Optimize the Therapeutic Strategy in Patients With Organizing Pneumonia Post-COVID-19
NCT04534478 ·Status: UNKNOWN ·Phase: PHASE4
-
COVID-19 Epidemic Response Study
NCT04357496 ·Status: WITHDRAWN
-
Efficacy of Early Administration of Tocilizumab in COVID-19 Patients
NCT04346355 ·Status: TERMINATED ·Phase: PHASE2