Is Long-term Use of Amantadine Effective in PD?
NCT04260581 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2020-02-07
Summary
The investigator aims to assess whether long-term use of amantadine is effective in patients with Parkinson's disease.
Conditions
- Parkinson Disease
Interventions
- DRUG
-
Determination of drug effects through amantadine cessation
Patients will discontinue amantadine, which has been taken since beginning of diagnosis.
Sponsors & Collaborators
-
Seoul National University Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-03-01
- Primary Completion
- 2021-02-28
- Completion
- 2021-02-28
Countries
- South Korea
Study Locations
More Related Trials
-
Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID.
NCT02153645 ·Status: TERMINATED ·Phase: PHASE3
-
A Phase 3, Long-term, Extension Study of TVP-1012 (1 mg) in Early Parkinson's Disease Participants
NCT02337751 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of IV Amantadine on Freezing of Gait (FOG) Resistant to Dopaminergic Therapy
NCT01313819 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to Evaluate the Safety, Tolerability and Efficacy of MT101-5 in Subjects with Early Parkinson's Disease
NCT06175767 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Rotigotine in the Treatment of Patients With Early Stage of Primary Parkinson's Disease
NCT04455555 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Amantadine Hydrogen Chloride (HCl) ER Tablets in Parkinson's Disease Subjects With LID
NCT02153632 ·Status: TERMINATED ·Phase: PHASE3
-
A Long-term, Phase 3 Study of TVP-1012 (1 mg) in Levodopa Treated Parkinson's Disease Participants
NCT02337764 ·Status: COMPLETED ·Phase: PHASE3
-
Multiple Ascending Dose Study of MEDI1341 in Patients With Parkinson's Disease
NCT04449484 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate DNL151 in Subjects With Parkinson's Disease
NCT04056689 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of the Efficacy and Safety of Modified Release AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
NCT01491529 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease
NCT01108029 ·Status: COMPLETED ·Phase: PHASE4
-
A 2-Part Trial of CVL-751 in Subjects With Parkinson's Disease
NCT04295642 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of the Efficacy and Safety of AFQ056 in Reducing Moderate to Severe L-dopa Induced Dyskinesias in Patients With Parkinson's Disease
NCT00986414 ·Status: COMPLETED ·Phase: PHASE2
-
An Open-Label Extension Trial to Assess the Safety and Tolerability of Long Term Treatment of Rotigotine in Subjects With Idiopathic Parkinson's Disease
NCT00505687 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Efficacy and Safety of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias
NCT01385592 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease
NCT06585449 ·Status: RECRUITING ·Phase: PHASE1
-
Pilot Study of Maintenance Therapy With Intravenous AMANTADINE
NCT01190553 ·Status: UNKNOWN ·Phase: NA
-
Amantadine and L-DOPA-induced Dyskinesia in Early Parkinson's Disease
NCT01538329 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial to Evaluate the Pharmacodynamics/Pharmacokinetics and Safety of LY03003 in Early PD Patients
NCT04629404 ·Status: COMPLETED ·Phase: PHASE1
-
Trial to Evaluate the Pharmacokinetics, Safety, and Tolerability of Rotigotine in Healthy Korean Subjects
NCT01964573 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects
NCT06216054 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Test the Safety, Tolerability, and Pharmacokinetics of UCB0599 in Healthy Study Participants and Patients With Parkinson's Disease (PD)
NCT04875962 ·Status: COMPLETED ·Phase: PHASE1
-
Lu AF28996 in Participants With Parkinson's Disease (PD)
NCT04291859 ·Status: COMPLETED ·Phase: PHASE1
-
Long-Term Effects of Amantadine in Parkinsonian (AMANDYSK)
NCT00632762 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Long-acting Levodopa on Obstructive Sleep Apnea in Parkinson's Disease
NCT03111485 ·Status: COMPLETED ·Phase: PHASE4