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High Dose Accelerated iTBS for Depression

NCT04255784 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 228

Last updated 2025-01-29

No results posted yet for this study

Summary

This trial will compare active intermittent theta burst stimulation (iTBS) rTMS in an accelerated treatment schedule (8 treatment sessions per day for 5 days) to a placebo control. Depression symptom severity will be measured before, during, at end of treatment, 1-week post and 4-weeks post treatment.

Conditions

Interventions

DEVICE

Active iTBS

Fluid-Cooled B70 A/P Coil with either Magventure X100 or R30

DEVICE

Sham iTBS

Fluid-Cooled B70 A/P Coil with either Magventure X100 or R30

Sponsors & Collaborators

  • University Health Network, Toronto

    collaborator OTHER

  • University of British Columbia

    collaborator OTHER

  • Centre for Addiction and Mental Health

    lead OTHER

Principal Investigators

  • Daniel Blumberger, MD · CAMH

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-06
Primary Completion
2025-01-24
Completion
2025-01-24

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04255784 on ClinicalTrials.gov