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SIRS in Cyanotic and Acyanotic Children in Cardiac Surgery

NCT04254744 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 197

Last updated 2021-03-15

No results posted yet for this study

Summary

Systemic inflammatory response syndrome (SIRS) is frequently observed in children after open-heart surgery and has been associated with both cardiopulmonary bypass and surgical trauma. Children with congenital cyanotic heart disease (CCHD) have complex changes in all blood values and clotting profiles due to chronic hypoxemia. Increased erythrocyte count decreases plasma and coagulation factors, platelet count and function. Therefore, blood and blood products transfusion may increase during intraoperative and postoperative periods. In addition, durations of cardiopulmonary bypass may prolong due to the complex defects of children with CCHD. The aim of this study is to investigate postoperative SIRS rates and risk factors in cyanotic and acyanotic children undergoing open heart surgery for congenital heart disease.

Conditions

  • SIRS
  • Pediatric Cardiac Surgery

Interventions

DRUG

Sevoflurane

Sevoflurane inhalation for anesthesia

Sponsors & Collaborators

  • Cukurova University

    lead OTHER

Eligibility

Min Age
1 Month
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-02-04
Primary Completion
2021-01-04
Completion
2021-02-04
FDA Drug
Yes

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04254744 on ClinicalTrials.gov