Association of Cefepime Trough Levels With Clinical Efficacy and Neurotoxicity in Patients With Febrile Neutropenia
NCT04250038 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 98
Last updated 2021-04-28
Summary
In this prospective monocenter observational study, the objective was to determine a safe and effective therapeutic window for cefepime in patients with neutropenic fever.
Conditions
- Pharmacokinetics
- Pharmacodynamics
- Cefepime
Sponsors & Collaborators
-
Universitaire Ziekenhuizen KU Leuven
lead OTHER
Principal Investigators
-
Isabel Spriet, PharmD PhD · UZ Leuven
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-08-01
- Primary Completion
- 2020-10-01
- Completion
- 2021-05-01
Countries
- Belgium
Study Locations
More Related Trials
-
Prospective Observational Study of Febrile Neutropenia (FN) and Pegfilgrastim Primary Prophylaxis in Breast Cancer and Non-Hodgkin's Lymphoma Patients Receiving High (>20%) FN-risk Chemotherapy
NCT02178475 ·Status: COMPLETED
-
Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder
NCT05689450 ·Status: COMPLETED
-
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia
NCT04910698 ·Status: COMPLETED
-
Fever and Neutropenia in Pediatric Oncology Patients
NCT03768869 ·Status: WITHDRAWN ·Phase: PHASE3
-
An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca
NCT04662892 ·Status: UNKNOWN
-
Early Antibiotic Discontinuation in FUO
NCT02906254 ·Status: COMPLETED
-
Study Investigating How Physicians Assess the Risk of Patients Developing Febrile Neutropenia During Chemotherapy.
NCT01813721 ·Status: COMPLETED
-
Safety and Efficacy of Ambulatory Versus In-hospital Antibiotic Treatment in Children With Febrile Neutropenia
NCT04000711 ·Status: COMPLETED ·Phase: NA
-
AMS Intervention for Early Adaptation of Empirical Antibiotic Therapy in High-risk Neutropenic Patients
NCT05793073 ·Status: COMPLETED
-
Antimicrobial Revision in Persistent Febrile Neutropenia
NCT05784844 ·Status: WITHDRAWN ·Phase: PHASE4
-
Observational Non-Interventional Study Of Febrile Neutropenia Patients To Evaluate Antibacterial Therapeutical Options
NCT00945555 ·Status: COMPLETED
-
Short-term Antibiotic Treatment for Unexplained Fever in Solid Cancer Patients With Febrile Neutropenia
NCT01450241 ·Status: WITHDRAWN ·Phase: NA
-
Risk Assessment of Febrile Neutropenia and Grade 3-4 Neutropenia in Patients With Non-hematological Cancer Treated With Conventional Chemotherapy
NCT01799421 ·Status: COMPLETED
-
Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia
NCT01484015 ·Status: COMPLETED ·Phase: PHASE1
-
The Oral Cavity as a Source of Febrile Neutropenia
NCT02702583 ·Status: COMPLETED
-
Comparison of 2 Antifungal Treatment (Empirical Versus Pre-Empirical) Strategies in Prolonged Neutropenia
NCT00190463 ·Status: TERMINATED ·Phase: PHASE4
-
Study Comparing the Safety and Efficacy of Piperacillin/Tazobactam to Cefepime in Patients With Hematologic Malignancy or Lymphoma
NCT00044759 ·Status: COMPLETED ·Phase: PHASE3
-
Short Antibiotic Treatment in High Risk Febrile Neutropenia
NCT05786495 ·Status: RECRUITING ·Phase: NA
-
Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients
NCT05665478 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia
NCT00020865 ·Status: UNKNOWN ·Phase: PHASE3
-
Daptomycin Versus Placebo in Patients With Neutropenia and Fever
NCT01216241 ·Status: TERMINATED ·Phase: PHASE3
-
A Trial of Fosfomycin vs Ciprofloxacin for Febrile Neutropenia
NCT05311254 ·Status: UNKNOWN ·Phase: PHASE3
-
Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia
NCT00445497 ·Status: UNKNOWN ·Phase: PHASE3
-
Granulocyte-colony Stimulating Factors or Antibiotics for Primary Prophylaxis for Febrile Neutropenia
NCT02816112 ·Status: COMPLETED ·Phase: PHASE4
-
Pediatric FN Definition 2012 Bern
NCT01683370 ·Status: COMPLETED