Trial Outcomes & Findings for E-learning+ Rehab Therapy (NCT NCT04245449)

NCT ID: NCT04245449

Last Updated: 2023-03-17

Results Overview

Health Literacy will be assessed via a standardize 18-item test designed to assess an adult's ability to read and understand common medical terms. Minimum = 0, Maximum = 18. Higher scores indicate greater health literacy.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

7 participants

Primary outcome timeframe

Baseline Visit and 3 months

Results posted on

2023-03-17

Participant Flow

Participants were enrolled however the study is designed so that cohorts start together. Study procedures did not start until a group of subjects were enrolled. Due to Covid shutting the study down study procedures did not start.

Participant milestones

Participant milestones
Measure
e Learning+Therapy (TEAACH)
TEAACH-Training to Empower Activity-dependent plasticity-based Arm-use habits in the Community and at Home TEAACH: TEAACH e-learning: 3-months of online educational modules include neuroscience education (based on an effective pain educational model37) to improve patient self-efficacy, and strategy-training38 to improve patients' problem-solving abilities for at-home arm use. The course is live on the MUSC MoodleCE platform. TEAACH in-clinic therapy: 24 in-clinic sessions; 3 times/week for 4 weeks (month 1), 2 times/week for 4 weeks (month 2) and 1 time/week for 4 weeks (month 3) with 200 movement repetitions per session. In our RCTs, this therapy dose required \~1.0-1.5 hours/session. A critical element of TEAACH is the focus on linking in-clinic therapy to out-of-clinic real world paretic arm use via MoodleCE Learning Activities.
Overall Study
STARTED
7
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
7

Reasons for withdrawal

Reasons for withdrawal
Measure
e Learning+Therapy (TEAACH)
TEAACH-Training to Empower Activity-dependent plasticity-based Arm-use habits in the Community and at Home TEAACH: TEAACH e-learning: 3-months of online educational modules include neuroscience education (based on an effective pain educational model37) to improve patient self-efficacy, and strategy-training38 to improve patients' problem-solving abilities for at-home arm use. The course is live on the MUSC MoodleCE platform. TEAACH in-clinic therapy: 24 in-clinic sessions; 3 times/week for 4 weeks (month 1), 2 times/week for 4 weeks (month 2) and 1 time/week for 4 weeks (month 3) with 200 movement repetitions per session. In our RCTs, this therapy dose required \~1.0-1.5 hours/session. A critical element of TEAACH is the focus on linking in-clinic therapy to out-of-clinic real world paretic arm use via MoodleCE Learning Activities.
Overall Study
COVID shutdown
7

Baseline Characteristics

E-learning+ Rehab Therapy

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
e Learning+Therapy (TEAACH)
n=7 Participants
TEAACH-Training to Empower Activity-dependent plasticity-based Arm-use habits in the Community and at Home TEAACH: TEAACH e-learning: 3-months of online educational modules include neuroscience education (based on an effective pain educational model37) to improve patient self-efficacy, and strategy-training38 to improve patients' problem-solving abilities for at-home arm use. The course is live on the MUSC MoodleCE platform. TEAACH in-clinic therapy: 24 in-clinic sessions; 3 times/week for 4 weeks (month 1), 2 times/week for 4 weeks (month 2) and 1 time/week for 4 weeks (month 3) with 200 movement repetitions per session. In our RCTs, this therapy dose required \~1.0-1.5 hours/session. A critical element of TEAACH is the focus on linking in-clinic therapy to out-of-clinic real world paretic arm use via MoodleCE Learning Activities.
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
7 Participants
n=99 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
Sex: Female, Male
Female
5 Participants
n=99 Participants
Sex: Female, Male
Male
2 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
7 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
Race (NIH/OMB)
Asian
0 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
4 Participants
n=99 Participants
Race (NIH/OMB)
White
3 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Region of Enrollment
United States
7 participants
n=99 Participants

PRIMARY outcome

Timeframe: Baseline Visit and 3 months

Population: Although the first subject was enrolled in August 2019, the Project was designed so that a cohort started together. In other words, the study team could not start study procedures until we had a group of subjects enrolled. Hence, although the first participant was enrolled in August, the study team was not able to start the study, because of the covid shut down in March prior to beginning the group related study procedures.

Health Literacy will be assessed via a standardize 18-item test designed to assess an adult's ability to read and understand common medical terms. Minimum = 0, Maximum = 18. Higher scores indicate greater health literacy.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Baseline and 3 months

Population: Although the first subject was enrolled in August 2019, the Project was designed so that a cohort started together. In other words, the study team could not start study procedures until we had a group of subjects enrolled. Hence, although the first participant was enrolled in August, the study team was not able to start the study, because of the covid shut down in March prior to beginning the group related study procedures.

Participants' ability to manage their chronic condition (their stroke) will be assessed qualitatively using interview questions. Participants' narratives will be analyzed and reported as a description of how their own skills have changed.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline Visit, 3 months and 5 months

Population: Although the first subject was enrolled in August 2019, the Project was designed so that a cohort started together. In other words, the study team could not start study procedures until we had a group of subjects enrolled. Hence, although the first participant was enrolled in August, the study team was not able to start the study, because of the covid shut down in March prior to beginning the group related study procedures.

Self-Efficacy will be assessed using the NIH PROMIS Self-Efficacy for Managing Daily Activities assessment. Minimum score = 0, Maximum score = 8. Higher numbers indicate greater self efficacy.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline Visit, 3 months & 5 months

Population: Although the first subject was enrolled in August 2019, the Project was designed so that a cohort started together. In other words, the study team could not start study procedures until we had a group of subjects enrolled. Hence, although the first participant was enrolled in August, the study team was not able to start the study, because of the covid shut down in March prior to beginning the group related study procedures.

Social Isolation will be assessed using the NIH PROMIS Social Isolation assessment. Minimum score = 0, Maximum score = 8. Higher numbers indicate less social isolation.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline Visit, 3 months (Post Treatment+/- 3 days), & 5 months (Follow up +/- 3 days)

Population: Although the first subject was enrolled in August 2019, the Project was designed so that a cohort started together. In other words, the study team could not start study procedures until we had a group of subjects enrolled. Hence, although the first participant was enrolled in August, the study team was not able to start the study, because of the covid shut down in March prior to beginning the group related study procedures.

Emotional Support will be assessed using the NIH PROMIS Emotional Support assessment. Minimum score = 0, Maximum score = 8. Higher numbers indicate greater emotional support.

Outcome measures

Outcome data not reported

Adverse Events

e Learning+Therapy (TEAACH)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Michelle Woodbury, PhD

Medical University of South Carolina

Phone: 843-792-0651

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place