Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF
NCT04244825 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2021-03-04
Summary
A Phase 2a, Double-Blind, Placebo-Controlled Study to Evaluate Pharmacodynamics, Pharmacokinetics, and Safety of BLD-2660 Administered Orally in Subjects with Idiopathic Pulmonary Fibrosis
Conditions
Interventions
- DRUG
-
BLD-2660
BLD-2660 - 150 mg capsules '00' size (PO) BID
- DRUG
-
Control: Placebo
Placebo - 150 mg capsules '00' size (PO) BID
Sponsors & Collaborators
-
Blade Therapeutics
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-12-15
- Primary Completion
- 2020-09-14
- Completion
- 2020-11-05
Countries
- United Kingdom
Study Locations
More Related Trials
-
Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Inhaled TPI 1100 in Healthy Volunteers
NCT00914433 ·Status: WITHDRAWN ·Phase: PHASE1
-
TD-0903 for ALI Associated With COVID-19
NCT04402866 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Test How Taking BI 1015550 for 12 Weeks Affects Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)
NCT04419506 ·Status: COMPLETED ·Phase: PHASE2
-
SB17170 Phase 2 Trial in IPF Patients
NCT06747923 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF)
NCT01203943 ·Status: TERMINATED ·Phase: PHASE2
-
Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis
NCT04396756 ·Status: COMPLETED ·Phase: PHASE2
-
TD-1058 First-In-Human Study in Healthy Subjects and Subjects With Idiopathic Pulmonary Fibrosis
NCT04589260 ·Status: TERMINATED ·Phase: PHASE1
-
A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care
NCT03733444 ·Status: TERMINATED ·Phase: PHASE3
-
This Study Tests Different Doses of BI 1015550 in Patients With Idiopathic Pulmonary Fibrosis (IPF). The Study Tests How BI 1015550 is Taken up by the Body and How Well it is Tolerated.
NCT03422068 ·Status: COMPLETED ·Phase: PHASE1
-
To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF
NCT05497284 ·Status: TERMINATED ·Phase: PHASE2
-
A Study Measuring the Effectiveness, Safety, and Tolerability of BMS-986278 in Participants With Lung Fibrosis
NCT04308681 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis
NCT02345070 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Effect of GBT440 Administered to Subjects With IPF on Supplemental Oxygen at Rest
NCT02989168 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 2 Study to Evaluate the Safety and Tolerability of PBI-4050 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
NCT02538536 ·Status: COMPLETED ·Phase: PHASE2
-
PH-797804 LPS Study in Healthy Volunteers
NCT02084485 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study to Assess Safety, Tolerability, PK and PD of AGMB-447 in Healthy Participants and Participants With IPF
NCT06181370 ·Status: RECRUITING ·Phase: PHASE1
-
A Clinical Trial on the Treatment of Idiopathic Pulmonary Fibrosis
NCT06102083 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study to Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of GLPG1690 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
NCT02738801 ·Status: COMPLETED ·Phase: PHASE2
-
Nintedanib Twice Daily vs Placebo in Patients Diagnosed With Idiopathic Pulmonary Fibrosis (IPF)
NCT01979952 ·Status: COMPLETED ·Phase: PHASE3
-
Study on Intravenous Injection of SHR-1906 in the Treatment of Idiopathic Pulmonary Fibrosis
NCT05722964 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 1b Study of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
NCT01254409 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy, Safety, and Tolerability of PIPE 791 in Subjects With Idiopathic Pulmonary Fibrosis
NCT07284459 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MNKD-201 in Patients With Idiopathic Pulmonary Fibrosis
NCT07344558 ·Status: RECRUITING ·Phase: PHASE1
-
Safety, Tolerability, and Efficacy Study of Idiopathic Pulmonary Fibrosis
NCT01262001 ·Status: COMPLETED ·Phase: PHASE2
-
Single Dose Lipopolysaccharide (LPS) Study In Healthy Volunteers
NCT01314885 ·Status: COMPLETED ·Phase: PHASE1