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Validation of a Novel Cortical Biomarker Signature for Pain

NCT04241562 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 159

Last updated 2023-04-04

No results posted yet for this study

Summary

The study aims to undertake analytical validation of an brain biomarker in healthy participants experiencing a model of sustained temporomandibular pain. The biomarker could detect participants at greater risk of developing more severe pain.

Conditions

  • TMD

Interventions

OTHER

Injection of Nerve Growth Factor

Injection of Nerve Growth Factor to the right masseter

Sponsors & Collaborators

  • Neuroscience Research Australia

    collaborator OTHER

  • University of Maryland, Baltimore

    lead OTHER

Principal Investigators

  • David A Seminowicz, PhD · University of Maryland School of Dentistry

  • Siobhan M Schabrun, PhD · Neuroscience Research Australia; University of New South Wales

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-11-04
Primary Completion
2022-10-10
Completion
2022-10-10

Countries

  • United States
  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04241562 on ClinicalTrials.gov