Trial Outcomes & Findings for Piloting a Novel Peer Support Pain Self-Management Intervention (Project CONNECT) (NCT NCT04229134)

NCT ID: NCT04229134

Last Updated: 2026-09-02

Results Overview

Post-treatment follow-up retention rates and their 95% confidence intervals. These will be compared to 80%, which is the lowest rate obtained in a behavioral pain trial and comparable to peer support interventions

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

4 participants

Primary outcome timeframe

3 months post baseline

Results posted on

2026-09-02

Participant Flow

Participant milestones

Participant milestones
Measure
Pilot Arm: Project CONNECT
8-week home based reciprocal peer support pain self-management program for chronic musculoskeletal pain
Overall Study
STARTED
4
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
4

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Piloting a Novel Peer Support Pain Self-Management Intervention (Project CONNECT)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Pilot Arm: Project CONNECT
n=4 Participants
8-week home based reciprocal peer support pain self-management program for chronic musculoskeletal pain
Age, Continuous
41.67 Years
STANDARD_DEVIATION 12.58 • n=136 Participants
Sex: Female, Male
Female
4 Participants
n=136 Participants
Sex: Female, Male
Male
0 Participants
n=136 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=136 Participants
Race (NIH/OMB)
Asian
0 Participants
n=136 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=136 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=136 Participants
Race (NIH/OMB)
White
3 Participants
n=136 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=136 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=136 Participants
Region of Enrollment
United States
4 Participants
n=136 Participants

PRIMARY outcome

Timeframe: 3 months post baseline

Post-treatment follow-up retention rates and their 95% confidence intervals. These will be compared to 80%, which is the lowest rate obtained in a behavioral pain trial and comparable to peer support interventions

Outcome measures

Outcome measures
Measure
Pilot Arm: Project CONNECT
n=4 Participants
8-week home based reciprocal peer support pain self-management program for chronic musculoskeletal pain
Feasibility: Retention
0 Percent of participants retained
Interval 0.0 to 0.75

PRIMARY outcome

Timeframe: 6 months post-baseline

Long-term follow-up retention rates and their 95% confidence intervals. These will be compared to 80%, which is the lowest rate obtained in a behavioral pain trial and comparable to peer support interventions

Outcome measures

Outcome measures
Measure
Pilot Arm: Project CONNECT
n=4 Participants
8-week home based reciprocal peer support pain self-management program for chronic musculoskeletal pain
Feasibility: Long-term Retention
0 percent participants retained
Interval 0.0 to 0.75

SECONDARY outcome

Timeframe: 3 months post baseline

Rates of successful dyad connection will be compared to 80% (comparable to other Reciprocal Peer Support interventions)

Outcome measures

Outcome measures
Measure
Pilot Arm: Project CONNECT
n=4 Participants
8-week home based reciprocal peer support pain self-management program for chronic musculoskeletal pain
Feasibility: Dyad Connection
0 percentage of participants paired
Interval 0.0 to 0.5

SECONDARY outcome

Timeframe: 3 months post baseline

Population: There were no participants who were successfully paired and enrolled in the intervention so participants did not complete diaries

Nightly assessment completion rates and their 95% confidence intervals will be compared to other Veteran behavioral pain trials demonstrating an 85% completion rate.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months post baseline

Population: There were no participants paired, thus they did not proceed to the intervention. Because of this, there was no data collected on skill practice

Skill practice rates and their 95% confidence intervals will also be compared to 65% consistent with rates reported in similar pain trials.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months post baseline

Population: There were no participants paired, thus they did not proceed to the intervention. Because of this, there was no data collected on acceptability or satisfaction

Mean intervention satisfaction and credibility ratings and their 95% confidence intervals will be compared to 80% which is the standard for behavioral pain trials

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months post baseline

Population: There were no participants paired, thus they did not proceed to the intervention. Because of this, there was no data collected on the acceptability of the peer matching

Favorable experience with peer ratings and their 95% confidence intervals will be compared with 80% which is comparable to other reciprocal peer support interventions

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months post baseline

Population: There were no participants paired, thus they did not proceed to the intervention. Because of this, there was no data collected

A responder analysis will be completed to determine percent of subjects achieving a clinically meaningful reduction in pain intensity, pain interference and depression. For both the Brief Pain Inventory Pain Intensity and Pain Interference subscales, a 30% reduction is defined as clinically meaningful. For depressive symptoms, a reduction of 5 points on the Patient Health questionnaire-8 is considered clinically meaningful

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months post baseline

Population: There were no participants paired, thus they did not proceed to the intervention. Because of this, there was no data collected on skill practice

A responder analysis will be completed to determine percent of subjects achieving a clinically meaningful reduction in pain intensity, pain interference and depression. For both the Brief Pain Inventory Pain Intensity and Pain Interference subscales, a 30% reduction is defined as clinically meaningful. For depressive symptoms, a reduction of 5 points on the Patient Health questionnaire-8 is considered clinically meaningful

Outcome measures

Outcome data not reported

Adverse Events

Pilot Arm: Project CONNECT

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Mary Driscoll, PhD

VA Connecticut Healthcare System

Phone: 203.228.0885

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place