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Serological Screen and Treat Trial for Plasmodium Vivax

NCT04223674 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1133

Last updated 2023-03-07

No results posted yet for this study

Summary

This is a clinical trial to evaluate an experimental serological diagnostic technique intended to identify people at high risk of having dormant malaria parasites in their liver. The study is designed to evaluate the efficacy of serological screening vs. routine care for the prevention of recurrent P. vivax infections. A total of 960 schoolchildren will be randomized into the interventional or control arm.

Conditions

  • Malaria, Vivax

Interventions

DIAGNOSTIC_TEST

Serological screen and treat

Multi-antigen sero-diagnostic test for measurement of P. vivax antibodies in plasma from finger stick as a means to detect hypnozoite carriers for treatment

Sponsors & Collaborators

  • Eijkman Institute for Molecular Biology

    collaborator OTHER

  • Oxford University Clinical Research Unit Indonesia

    collaborator OTHER

  • Walter and Eliza Hall Institute of Medical Research

    collaborator OTHER

  • Rumah Sakit Umum Daerah Mimika

    collaborator UNKNOWN

  • Universitas Sumatera Utara

    collaborator OTHER

  • Indonesia University

    lead OTHER

Principal Investigators

  • Inge Sutanto, MD, PhD · Indonesia University

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-02-09
Primary Completion
2023-05-30
Completion
2023-12-30

Countries

  • Indonesia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04223674 on ClinicalTrials.gov