MedTrace Logo

Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon

NCT04205669 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 104

Last updated 2020-11-13

Study results available
· View outcomes & findings →

Summary

It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study therefore compares these two treatment strategies with topical benzyl benzoate for treating scabies in Lambaréné and surroundings in Gabon.

Subjects presenting with uncomplicated scabies are randomized into either the Individual Treatment group, where only the affected subjects receive treatment, or the Household Treatment group, where all family members are treated in parallel to the affected subjects regardless of signs and symptoms. The primary endpoint is clinical cure after 28 days; the secondary endpoint is the proportion of affected household members per household after 28 days.

Conditions

  • Scabies
  • Households

Interventions

DRUG

Benzyl Benzoate 25% Topical Application Lotion

Applied to skin for the treatment of scabies

Sponsors & Collaborators

  • Bernhard Nocht Institute for Tropical Medicine

    collaborator OTHER_GOV

  • University Hospital Tuebingen

    collaborator OTHER

  • Medical University of Vienna

    collaborator OTHER

  • Centre de Recherche Médicale de Lambaréné

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-04
Primary Completion
2019-02-21
Completion
2019-02-21

Countries

  • Gabon

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04205669 on ClinicalTrials.gov