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Peri-vascular Adipose Tissue Inflammation Evaluated Using Coronary CT Angiography

NCT04181749 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2023-12-19

No results posted yet for this study

Summary

The P-VECT Study proposes to test the use of CCTA-derived FAI measurements in a group of patients with coronary artery inflammation, who will receive routinely-used statin and aspirin treatment. The P-VECT Study is a pilot study that will provide the rationale and data for power calculations to enable design of pivotal trials of the clinical effectiveness of FAI.

Conditions

  • Cardiovascular Risk Factor

Interventions

DRUG

aspirin and atorvastatin

Patients will be randomized and prescribed either no treatment or aspirin 75mg and Atorvastatin 40mg

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • British Heart Foundation

    collaborator OTHER

  • National Institute for Health Research, United Kingdom

    collaborator OTHER_GOV

  • University of Leicester

    lead OTHER

Principal Investigators

  • David Adlam, Dr. · University Hospitals of Leicester and University of Leicester

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-18
Primary Completion
2024-01-31
Completion
2024-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04181749 on ClinicalTrials.gov