MitraClip EXPAND G4 Study
NCT04177394 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1164
Last updated 2025-07-11
Summary
This primary objective of the EXPAND G4 study is to confirm the safety and performance of the MitraClip G4 System in a post-market setting.
Conditions
- Mitral Valve Regurgitation
- Mitral Regurgitation
Interventions
- DEVICE
-
MitraClip G4 System
Percutaneous mitral valve repair using the MitraClip G4 system.
Sponsors & Collaborators
- collaborator INDUSTRY
-
Abbott Medical Devices
lead INDUSTRY
Principal Investigators
-
Kartik Sundareswaran, PhD · Abbott Structural Heart
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-17
- Primary Completion
- 2022-05-19
- Completion
- 2028-03-31
- FDA Device
- Yes
Countries
- United States
- Canada
- France
- Germany
- Israel
- Italy
- Japan
- Netherlands
- Saudi Arabia
- Spain
Study Locations
More Related Trials
-
The CardioClip Study
NCT06241430 ·Status: RECRUITING ·Phase: NA
-
Mitral Regurgitation Treatment in Advanced Heart Failure
NCT05292716 ·Status: RECRUITING ·Phase: NA
-
MitraClip China PMS
NCT04259411 ·Status: COMPLETED ·Phase: NA
-
Confirmatory Clinical Study of Treating Tricuspid Regurgitation With K-Clip TM Transcatheter Annuloplasty System
NCT05173233 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)
NCT02592889 ·Status: UNKNOWN ·Phase: PHASE4
-
Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation
NCT05797519 ·Status: RECRUITING ·Phase: NA
-
MitraClip® Registry
NCT02033811 ·Status: RECRUITING
-
A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation
NCT01772108 ·Status: TERMINATED ·Phase: NA
-
High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgical Therapy
NCT02534155 ·Status: TERMINATED ·Phase: PHASE4
-
Multiparametric Protocol for Assessment of Intraprocedural Result of MITRACLIP Procedure
NCT06184789 ·Status: RECRUITING
-
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS
NCT01626079 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
MitraClip® After Surgical Mitral Valve Repair
NCT02853955 ·Status: UNKNOWN
-
Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDER
NCT00578708 ·Status: COMPLETED ·Phase: PHASE1
-
ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe
NCT01288976 ·Status: COMPLETED
-
MiCLASP Post Market Clinical Follow-Up (PMCF) Study
NCT04430075 ·Status: RECRUITING
-
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
NCT07227675 ·Status: COMPLETED ·Phase: NA
-
Safety and Effectiveness Study of SQ-Kyrin System for Functional Mitral Regurgitation in EU
NCT06823700 ·Status: RECRUITING ·Phase: NA
-
GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4
NCT05455489 ·Status: RECRUITING
-
AltaValve Pivotal Trial
NCT06465745 ·Status: RECRUITING ·Phase: NA
-
Noninferiority Trial of MitraClip Implantation Strategies: 1 Clip vs. 2 Clips in Patients With Functional Mitral Regurgitation
NCT03503851 ·Status: WITHDRAWN ·Phase: NA
-
Strain Imaging in Patients With Functional Mitral Regurgitation, Treated With MitraClip
NCT04218578 ·Status: COMPLETED
-
MitraClip REPAIR MR Study
NCT04198870 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluation of Outcomes of CRT and MitraClip for Treatment of Low Ejection Fraction and Functional Mitral Regurgitation in HF
NCT02985268 ·Status: WITHDRAWN ·Phase: NA
-
MitraClip in Patients With Heart Failure
NCT06633159 ·Status: RECRUITING
-
The CINCH-FMR Post-Market Registry: Percutaneous Repair in Functional Mitral Regurgitation
NCT05677568 ·Status: ENROLLING_BY_INVITATION