Binding of Foliglurax to Regions in the Brain in Healthy Participants and in Patients With Parkinson's Disease (PD)
NCT04175132 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2020-12-09
Summary
A study to learn how foliglurax binds in regions of the brain
Conditions
- Healthy
- Parkinson Disease
Interventions
- DRUG
-
foliglurax
Capsules of 20/80 mg foliglurax, orally. Single doses of 20-240 mg
- DRUG
-
foliglurax
Capsules of 20/80 mg foliglurax, orally. Single doses of 20-160 mg
Sponsors & Collaborators
-
H. Lundbeck A/S
lead INDUSTRY
Principal Investigators
-
Email contact via H. Lundbeck A/S · [email protected]
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 50 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-11-12
- Primary Completion
- 2020-03-03
- Completion
- 2020-03-10
Countries
- Sweden
Study Locations
More Related Trials
-
Prognostic Values of PET Examination With 11 C-Fe_CIT With Voxel-based Analysis Method in Patients With Sporadic Parkonson's Disease and Parkinsonisms (Prot.PD-diagn).
NCT06171451 ·Status: COMPLETED
-
11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes
NCT03555292 ·Status: UNKNOWN ·Phase: PHASE2
-
An Open-label, Observational, Long-term Follow-up Study Evaluating the Safety and Efficacy of RGL-193 Putamen Injection in Patients With Primary Parkinson's Disease
NCT07279844 ·Status: NOT_YET_RECRUITING
-
Long-Term Vesicular Monoamine Transporter II Imaging and Clinical Assessment of Parkinson's Disease Progression
NCT01556100 ·Status: COMPLETED ·Phase: PHASE2
-
Characterizing the Specificity and Stability of Local Field Potentials in the Globus Pallidus Internus of Patients Undergoing Deep Brain Stimulation for Parkinson's Disease
NCT02438033 ·Status: WITHDRAWN ·Phase: PHASE1
-
Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders
NCT00001178 ·Status: TERMINATED
-
Parkinson's Disease Evaluated by PET and the Effect of Memantine
NCT00375778 ·Status: COMPLETED ·Phase: NA
-
Deep Brain Stimulation of the Subthalamic Nucleus (STN) and Cognitive Control
NCT00917722 ·Status: COMPLETED
-
PET Study in Parkinson's Disease Patients
NCT01527695 ·Status: COMPLETED ·Phase: PHASE2
-
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment
NCT00306124 ·Status: UNKNOWN ·Phase: PHASE4
-
Study of Motor Inhibition in Parkinson's Disease and Focal Hand Dystonia
NCT05209516 ·Status: UNKNOWN ·Phase: NA
-
A Feasibility Study on the Safety and Preliminary Efficacy of Bilateral Subthalamotomy Using MRgFUS for Treatment of PD
NCT03964272 ·Status: COMPLETED ·Phase: NA
-
Subthalamic Nucleus Connectivity in Parkinson's Disease With Ultra-high Field Magnetic Resonance Imaging
NCT01981577 ·Status: UNKNOWN
-
Asleep MRI-guided Versus Awake Microelectrode Recording Guided Deep Brain Stimulation in Parkinson's Disease: A Comparative Effectiveness Trial
NCT05453331 ·Status: UNKNOWN
-
ExAblate Transcranial MRgFUS of the Subthalamic Nucleus for Treatment of Parkinson's Disease
NCT02246374 ·Status: COMPLETED ·Phase: NA
-
A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate Transcranial MR Guided Focused Ultrasound for Unilateral Pallidotomy in the Treatment of Dyskinesia of Parkinson's Disease
NCT02003248 ·Status: COMPLETED ·Phase: PHASE1
-
Mapping Mood in the Subthalamic Nucleus in Parkinson's Disease (PD)
NCT00847431 ·Status: COMPLETED
-
Local Field Potentials Recorded From Deep Brain Stimulating (DBS) Electrodes
NCT01427530 ·Status: COMPLETED
-
Deep Brain Stimulation (DBS) of the Nucleus Basalis of Meynert (NbM) in Patients With Parkinson's Disease
NCT02763397 ·Status: UNKNOWN ·Phase: NA
-
Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait
NCT06994728 ·Status: RECRUITING ·Phase: NA
-
Cholinergic Mechanisms of Attentional-motor Integration and Gait Dysfunction in Parkinson Disease (UDALL)
NCT05459753 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Follow Up Study for Treatment of Parkinson's Disease With Subthalamic Deep Brain Stimulation
NCT03230331 ·Status: COMPLETED
-
Florbetapir F 18 PET Imaging of Beta-amyloid in Parkinson's Disease Patients
NCT00857532 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Motor Cortex Stimulation in the Treatment of Advanced Parkinson Disease
NCT00159172 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
18F-DTBZ for l Diagnosis of Parkinson's Disease and Monitoring the Severity of Disease by VMAT2 PET Imaging
NCT01283347 ·Status: COMPLETED ·Phase: PHASE2