Trial Outcomes & Findings for Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge (NCT NCT04168645)
NCT ID: NCT04168645
Last Updated: 2025-04-16
Results Overview
Suicidal behavior will be assessed using the Columbia Suicide Severity Rating Scale (C-SSRS), a widely used suicide assessment measure. Several suicidal behaviors are assessed on the C-SSRS including the presence or absence of each of the following: suicide attempt, interrupted attempt, aborted attempt, and preparatory acts or behaviors. Scores reflect the number of participants with the presence of the suicide behavior.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
213 participants
Primary outcome timeframe
Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.
Results posted on
2025-04-16
Participant Flow
Participant milestones
| Measure |
Presence of SUD With BCBT
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Overall Study
STARTED
|
62
|
65
|
41
|
45
|
|
Overall Study
Intent to Treat
|
56
|
64
|
38
|
42
|
|
Overall Study
COMPLETED
|
30
|
33
|
23
|
28
|
|
Overall Study
NOT COMPLETED
|
32
|
32
|
18
|
17
|
Reasons for withdrawal
| Measure |
Presence of SUD With BCBT
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Overall Study
Lost to Follow-up
|
23
|
28
|
15
|
12
|
|
Overall Study
Death
|
1
|
1
|
0
|
0
|
|
Overall Study
Withdrawal by Subject
|
5
|
2
|
2
|
2
|
|
Overall Study
Administrative Withdrawal
|
3
|
1
|
1
|
3
|
Baseline Characteristics
There was missing gender identity data for two participants.
Baseline characteristics by cohort
| Measure |
Presence of SUD With BCBT
n=62 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=65 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=41 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=45 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Total
n=213 Participants
Total of all reporting groups
|
|---|---|---|---|---|---|
|
Age, Continuous
|
34.00 years
STANDARD_DEVIATION 11.70 • n=62 Participants
|
32.68 years
STANDARD_DEVIATION 11.71 • n=65 Participants
|
33.22 years
STANDARD_DEVIATION 14.28 • n=41 Participants
|
32.09 years
STANDARD_DEVIATION 14.01 • n=45 Participants
|
33.04 years
STANDARD_DEVIATION 12.67 • n=213 Participants
|
|
Sex/Gender, Customized
Gender Identity · Male
|
24 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
32 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
13 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
12 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
81 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Female
|
30 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
28 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
23 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
26 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
107 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Trans Male
|
3 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
1 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
1 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
5 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Trans Female
|
2 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
1 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
1 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
2 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
6 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Genderqueer/Gender Non-Conforming
|
2 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
3 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
2 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
4 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
11 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Do Not Identify As Any of These Options
|
0 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Prefer Not to Answer
|
1 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
1 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex/Gender, Customized
Gender Identity · Missing
|
0 Participants
n=62 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=65 Participants • There was missing gender identity data for two participants.
|
2 Participants
n=41 Participants • There was missing gender identity data for two participants.
|
0 Participants
n=45 Participants • There was missing gender identity data for two participants.
|
2 Participants
n=213 Participants • There was missing gender identity data for two participants.
|
|
Sex: Female, Male
Female
|
34 Participants
n=61 Participants • There was missing sex assigned at birth data for one participant.
|
31 Participants
n=65 Participants • There was missing sex assigned at birth data for one participant.
|
27 Participants
n=41 Participants • There was missing sex assigned at birth data for one participant.
|
30 Participants
n=45 Participants • There was missing sex assigned at birth data for one participant.
|
122 Participants
n=212 Participants • There was missing sex assigned at birth data for one participant.
|
|
Sex: Female, Male
Male
|
27 Participants
n=61 Participants • There was missing sex assigned at birth data for one participant.
|
34 Participants
n=65 Participants • There was missing sex assigned at birth data for one participant.
|
14 Participants
n=41 Participants • There was missing sex assigned at birth data for one participant.
|
15 Participants
n=45 Participants • There was missing sex assigned at birth data for one participant.
|
90 Participants
n=212 Participants • There was missing sex assigned at birth data for one participant.
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
16 Participants
n=62 Participants
|
19 Participants
n=65 Participants
|
6 Participants
n=41 Participants
|
10 Participants
n=45 Participants
|
51 Participants
n=213 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
45 Participants
n=62 Participants
|
43 Participants
n=65 Participants
|
30 Participants
n=41 Participants
|
35 Participants
n=45 Participants
|
153 Participants
n=213 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
1 Participants
n=62 Participants
|
3 Participants
n=65 Participants
|
5 Participants
n=41 Participants
|
0 Participants
n=45 Participants
|
9 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · White
|
42 Participants
n=62 Participants
|
37 Participants
n=65 Participants
|
26 Participants
n=41 Participants
|
28 Participants
n=45 Participants
|
133 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Black or African American
|
6 Participants
n=62 Participants
|
9 Participants
n=65 Participants
|
7 Participants
n=41 Participants
|
8 Participants
n=45 Participants
|
30 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Asian
|
0 Participants
n=62 Participants
|
0 Participants
n=65 Participants
|
1 Participants
n=41 Participants
|
1 Participants
n=45 Participants
|
2 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Native Hawaiian or Pacific Islander
|
0 Participants
n=62 Participants
|
0 Participants
n=65 Participants
|
0 Participants
n=41 Participants
|
1 Participants
n=45 Participants
|
1 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · American Indian or Alaskan Native
|
1 Participants
n=62 Participants
|
1 Participants
n=65 Participants
|
1 Participants
n=41 Participants
|
0 Participants
n=45 Participants
|
3 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Multiracial
|
4 Participants
n=62 Participants
|
5 Participants
n=65 Participants
|
0 Participants
n=41 Participants
|
0 Participants
n=45 Participants
|
9 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Other
|
7 Participants
n=62 Participants
|
12 Participants
n=65 Participants
|
4 Participants
n=41 Participants
|
6 Participants
n=45 Participants
|
29 Participants
n=213 Participants
|
|
Race/Ethnicity, Customized
Race · Prefer Not to Answer
|
2 Participants
n=62 Participants
|
1 Participants
n=65 Participants
|
2 Participants
n=41 Participants
|
1 Participants
n=45 Participants
|
6 Participants
n=213 Participants
|
|
Region of Enrollment
United States
|
62 Participants
n=62 Participants
|
65 Participants
n=65 Participants
|
41 Participants
n=41 Participants
|
45 Participants
n=45 Participants
|
213 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Lifetime Actual Suicide Attempts
|
60 Participants
n=62 Participants
|
65 Participants
n=65 Participants
|
39 Participants
n=41 Participants
|
41 Participants
n=45 Participants
|
205 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Lifetime Interrupted Suicide Attempts
|
24 Participants
n=62 Participants
|
19 Participants
n=65 Participants
|
12 Participants
n=41 Participants
|
11 Participants
n=45 Participants
|
66 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Lifetime Aborted Suicide Attempts
|
16 Participants
n=62 Participants
|
20 Participants
n=65 Participants
|
12 Participants
n=41 Participants
|
18 Participants
n=45 Participants
|
66 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Lifetime Preparatory Events
|
24 Participants
n=62 Participants
|
32 Participants
n=65 Participants
|
13 Participants
n=41 Participants
|
23 Participants
n=45 Participants
|
92 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Past Month Most Severe Ideation
Active Suicidal Ideation with Any Methods
|
0 Participants
n=62 Participants
|
2 Participants
n=65 Participants
|
0 Participants
n=41 Participants
|
1 Participants
n=45 Participants
|
3 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Past Month Most Severe Ideation
Active Suicidal Ideation with Some Intent to Act
|
0 Participants
n=62 Participants
|
2 Participants
n=65 Participants
|
0 Participants
n=41 Participants
|
0 Participants
n=45 Participants
|
2 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Past Month Most Severe Ideation
Active Suicidal Ideation with Specific Plan
|
62 Participants
n=62 Participants
|
61 Participants
n=65 Participants
|
41 Participants
n=41 Participants
|
44 Participants
n=45 Participants
|
208 Participants
n=213 Participants
|
|
Columbia Suicide Severity Rating Scale Past Month Suicidal Ideation Intensity
|
19.18 units on a scale
STANDARD_DEVIATION 3.02 • n=62 Participants
|
18.17 units on a scale
STANDARD_DEVIATION 3.68 • n=65 Participants
|
18.05 units on a scale
STANDARD_DEVIATION 3.41 • n=41 Participants
|
18.04 units on a scale
STANDARD_DEVIATION 3.06 • n=45 Participants
|
18.42 units on a scale
STANDARD_DEVIATION 3.33 • n=213 Participants
|
PRIMARY outcome
Timeframe: Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.Population: Data were missing due to attrition.
Suicidal behavior will be assessed using the Columbia Suicide Severity Rating Scale (C-SSRS), a widely used suicide assessment measure. Several suicidal behaviors are assessed on the C-SSRS including the presence or absence of each of the following: suicide attempt, interrupted attempt, aborted attempt, and preparatory acts or behaviors. Scores reflect the number of participants with the presence of the suicide behavior.
Outcome measures
| Measure |
Presence of SUD With BCBT
n=53 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=57 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=38 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=41 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 2
|
3 Participants
|
4 Participants
|
0 Participants
|
3 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 3
|
1 Participants
|
4 Participants
|
0 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 4
|
0 Participants
|
2 Participants
|
0 Participants
|
3 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 5
|
2 Participants
|
3 Participants
|
2 Participants
|
1 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 6
|
1 Participants
|
2 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Post-treatment
|
0 Participants
|
0 Participants
|
0 Participants
|
1 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 1
|
0 Participants
|
2 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 2
|
0 Participants
|
2 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 4
|
0 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 6
|
0 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 1
|
1 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 2
|
1 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 3
|
0 Participants
|
2 Participants
|
0 Participants
|
1 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 6
|
1 Participants
|
0 Participants
|
2 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 2
|
0 Participants
|
1 Participants
|
1 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 3
|
0 Participants
|
1 Participants
|
2 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 4
|
1 Participants
|
2 Participants
|
2 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Post-treatment
|
1 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 1
|
1 Participants
|
4 Participants
|
0 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 3
|
2 Participants
|
1 Participants
|
0 Participants
|
1 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 5
|
0 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Post-treatment
|
1 Participants
|
1 Participants
|
0 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 4
|
0 Participants
|
0 Participants
|
0 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 5
|
1 Participants
|
0 Participants
|
0 Participants
|
0 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Post-treatment
|
1 Participants
|
1 Participants
|
1 Participants
|
2 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 1
|
1 Participants
|
3 Participants
|
0 Participants
|
4 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 5
|
1 Participants
|
0 Participants
|
0 Participants
|
1 Participants
|
|
Columbia Suicide Severity Rating Scale Number of Participants Reporting Presence of Suicidal Behaviors
Preparatory Events at Follow-up 6
|
1 Participants
|
0 Participants
|
2 Participants
|
0 Participants
|
PRIMARY outcome
Timeframe: Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.Population: Data were missing due to attrition.
Suicidal behavior will be assessed using the Columbia Suicide Severity Rating Scale (C-SSRS), a widely used suicide assessment measure. Several suicidal behaviors are assessed on the C-SSRS including the presence or absence of each of the following: suicide attempt, interrupted attempt, aborted attempt, and preparatory acts or behaviors. Scores on this scale reflect the median number of each behavior.
Outcome measures
| Measure |
Presence of SUD With BCBT
n=53 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=57 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=39 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=41 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Post-treatment
|
0.00 Number of Events
Standard Deviation 0.27
|
0.00 Number of Events
Standard Deviation 0.13
|
0.00 Number of Events
Standard Deviation 0.33
|
0.00 Number of Events
Standard Deviation 0.22
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 3
|
0.00 Number of Events
Standard Deviation 0.16
|
0.00 Number of Events
Standard Deviation 1.69
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.25
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 4
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.22
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.29
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 1
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.32
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 2
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.20
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 4
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.16
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 5
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.16
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 6
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.17
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 6
|
0.00 Number of Events
Standard Deviation 0.18
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.29
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 2
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.18
|
0.00 Number of Events
Standard Deviation 0.37
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 3
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.58
|
0.00 Number of Events
Standard Deviation 0.25
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 4
|
0.00 Number of Events
Standard Deviation 0.17
|
0.00 Number of Events
Standard Deviation 0.22
|
0.00 Number of Events
Standard Deviation 0.27
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 5
|
0.00 Number of Events
Standard Deviation 0.51
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.18
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 6
|
0.00 Number of Events
Standard Deviation 0.18
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.29
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Post-treatment
|
0.00 Number of Events
Standard Deviation 0.14
|
0.00 Number of Events
Standard Deviation 0.13
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 1
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.28
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.36
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 2
|
0.00 Number of Events
Standard Deviation 0.26
|
0.00 Number of Events
Standard Deviation 0.80
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.40
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 5
|
0.00 Number of Events
Standard Deviation 0.38
|
0.00 Number of Events
Standard Deviation 0.48
|
0.00 Number of Events
Standard Deviation 0.83
|
0.00 Number of Events
Standard Deviation 0.18
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Actual Suicide Attempt at Follow-up 6
|
0.00 Number of Events
Standard Deviation 0.18
|
0.00 Number of Events
Standard Deviation 0.38
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Post-treatment
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.16
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Interrupted Suicide Attempt at Follow-up 3
|
0.00 Number of Events
Standard Deviation 0.36
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.18
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Post-treatment
|
0.00 Number of Events
Standard Deviation 0.14
|
0.00 Number of Events
Standard Deviation 0.13
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.35
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 1
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.14
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 2
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 3
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.21
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.35
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 4
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.24
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Aborted Suicide Attempt at Follow-up 5
|
0.00 Number of Events
Standard Deviation 0.34
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.00
|
|
Columbia Suicide Severity Rating Scale Number of Suicidal Behaviors
Preparatory Events at Follow-up 1
|
0.00 Number of Events
Standard Deviation 0.15
|
0.00 Number of Events
Standard Deviation 1.23
|
0.00 Number of Events
Standard Deviation 0.00
|
0.00 Number of Events
Standard Deviation 0.31
|
PRIMARY outcome
Timeframe: Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.Population: Data were missing due to attrition.
The number of participants endorsing each category as the highest (most severe) suicidal ideation category on the Columbia Suicide Severity Rating Scale (C-SSRS) ranging from 1-5, with 5 being the most severe type of suicidal ideation.
Outcome measures
| Measure |
Presence of SUD With BCBT
n=53 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=56 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=38 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=41 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · Active Suicidal Ideation with Specific Plan
|
4 Participants
|
6 Participants
|
4 Participants
|
4 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · None
|
31 Participants
|
21 Participants
|
15 Participants
|
15 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · None
|
31 Participants
|
21 Participants
|
20 Participants
|
15 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · Wish to be Dead
|
7 Participants
|
16 Participants
|
8 Participants
|
4 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · Non-Specific Active Suicidal Thoughts
|
2 Participants
|
3 Participants
|
3 Participants
|
1 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · Active Suicidal Ideation with Any Methods
|
5 Participants
|
5 Participants
|
2 Participants
|
9 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · Active Suicidal Ideation with Some Intent to Act
|
1 Participants
|
3 Participants
|
0 Participants
|
2 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Post-treatment · Active Suicidal Ideation with Specific Plan
|
7 Participants
|
8 Participants
|
5 Participants
|
10 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · None
|
32 Participants
|
23 Participants
|
16 Participants
|
12 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · Wish to be Dead
|
3 Participants
|
11 Participants
|
8 Participants
|
11 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · Non-Specific Active Suicidal Thoughts
|
0 Participants
|
1 Participants
|
6 Participants
|
5 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · Active Suicidal Ideation with Any Methods
|
4 Participants
|
4 Participants
|
1 Participants
|
3 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · Active Suicidal Ideation with Some Intent to Act
|
2 Participants
|
0 Participants
|
1 Participants
|
1 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 1 · Active Suicidal Ideation with Specific Plan
|
5 Participants
|
8 Participants
|
2 Participants
|
4 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · None
|
28 Participants
|
24 Participants
|
14 Participants
|
18 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · Wish to be Dead
|
4 Participants
|
10 Participants
|
9 Participants
|
8 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · Non-Specific Active Suicidal Thoughts
|
0 Participants
|
2 Participants
|
1 Participants
|
2 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · Active Suicidal Ideation with Any Methods
|
4 Participants
|
4 Participants
|
4 Participants
|
2 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · None
|
24 Participants
|
25 Participants
|
16 Participants
|
18 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · Wish to be Dead
|
7 Participants
|
10 Participants
|
8 Participants
|
8 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · Non-Specific Active Suicidal Thoughts
|
0 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · Active Suicidal Ideation with Any Methods
|
2 Participants
|
3 Participants
|
1 Participants
|
0 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 3 · Active Suicidal Ideation with Some Intent to Act
|
0 Participants
|
0 Participants
|
0 Participants
|
2 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · Wish to be Dead
|
4 Participants
|
12 Participants
|
9 Participants
|
8 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · Non-Specific Active Suicidal Thoughts
|
0 Participants
|
0 Participants
|
0 Participants
|
3 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · Active Suicidal Ideation with Any Methods
|
0 Participants
|
2 Participants
|
1 Participants
|
1 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · Active Suicidal Ideation with Some Intent to Act
|
1 Participants
|
1 Participants
|
1 Participants
|
0 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 4 · Active Suicidal Ideation with Specific Plan
|
1 Participants
|
3 Participants
|
1 Participants
|
7 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · None
|
25 Participants
|
23 Participants
|
12 Participants
|
15 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · Wish to be Dead
|
4 Participants
|
7 Participants
|
5 Participants
|
6 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · Non-Specific Active Suicidal Thoughts
|
1 Participants
|
2 Participants
|
0 Participants
|
2 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · Active Suicidal Ideation with Any Methods
|
2 Participants
|
1 Participants
|
5 Participants
|
4 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · Active Suicidal Ideation with Some Intent to Act
|
0 Participants
|
1 Participants
|
0 Participants
|
1 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 5 · Active Suicidal Ideation with Specific Plan
|
2 Participants
|
3 Participants
|
2 Participants
|
3 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · None
|
24 Participants
|
18 Participants
|
13 Participants
|
15 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · Wish to be Dead
|
2 Participants
|
8 Participants
|
3 Participants
|
5 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · Non-Specific Active Suicidal Thoughts
|
0 Participants
|
1 Participants
|
1 Participants
|
3 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · Active Suicidal Ideation with Any Methods
|
1 Participants
|
3 Participants
|
3 Participants
|
4 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · Active Suicidal Ideation with Specific Plan
|
2 Participants
|
2 Participants
|
3 Participants
|
1 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · Active Suicidal Ideation with Some Intent to Act
|
1 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 2 · Active Suicidal Ideation with Specific Plan
|
5 Participants
|
6 Participants
|
2 Participants
|
5 Participants
|
|
The Number of Participants Reporting Columbia Suicide Severity Rating Scale Suicidal Ideation Categories as Most Severe
Most Severe Ideation at Follow-up 6 · Active Suicidal Ideation with Some Intent to Act
|
0 Participants
|
1 Participants
|
0 Participants
|
0 Participants
|
PRIMARY outcome
Timeframe: Assessed at completion of inpatient treatment (average of 12 days), and on a monthly basis for 6 months follow-up.Population: Data were missing due to attrition.
The Columbia Suicide Severity Rating Scale (C-SSRS) intensity subscale is the sum of 5 questions (frequency, duration, controllability, deterrents, and reasons for ideation) rated from 1-5, with 5 representing more severe intensity. Zero is entered if no suicidal ideation is reported. Total scores range from 0 to 25 with higher scores indicating more intense suicidal ideation.
Outcome measures
| Measure |
Presence of SUD With BCBT
n=52 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=56 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=38 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=41 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Post-treatment
|
6.04 score on a scale
Standard Deviation 7.60
|
9.68 score on a scale
Standard Deviation 7.94
|
6.84 score on a scale
Standard Deviation 7.69
|
10.29 score on a scale
Standard Deviation 8.32
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Follow-up 1
|
4.76 score on a scale
Standard Deviation 7.55
|
7.79 score on a scale
Standard Deviation 7.97
|
7.24 score on a scale
Standard Deviation 7.11
|
9.42 score on a scale
Standard Deviation 7.07
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Follow-up 2
|
4.48 score on a scale
Standard Deviation 6.84
|
6.60 score on a scale
Standard Deviation 7.45
|
8.23 score on a scale
Standard Deviation 8.71
|
7.86 score on a scale
Standard Deviation 8.67
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Follow-up 5
|
3.88 score on a scale
Standard Deviation 6.68
|
5.68 score on a scale
Standard Deviation 7.72
|
7.54 score on a scale
Standard Deviation 8.28
|
7.87 score on a scale
Standard Deviation 7.95
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicide Ideation at Follow-up 6
|
2.83 score on a scale
Standard Deviation 6.40
|
6.12 score on a scale
Standard Deviation 7.29
|
6.91 score on a scale
Standard Deviation 8.48
|
6.21 score on a scale
Standard Deviation 7.15
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Follow-up 3
|
4.47 score on a scale
Standard Deviation 6.78
|
6.76 score on a scale
Standard Deviation 8.17
|
6.59 score on a scale
Standard Deviation 7.78
|
6.81 score on a scale
Standard Deviation 8.17
|
|
Columbia Suicide Severity Rating Scale Suicidal Ideation Intensity Scale Total Score
Intensity of Suicidal Ideation at Follow-up 4
|
2.35 score on a scale
Standard Deviation 5.69
|
6.41 score on a scale
Standard Deviation 7.30
|
7.19 score on a scale
Standard Deviation 8.33
|
8.74 score on a scale
Standard Deviation 8.37
|
PRIMARY outcome
Timeframe: Assessed on a monthly basis for 6 months follow-up.Population: Missing data are due to participants dropping out of the study during the follow-up period.
Readmission is determined using the participant's electronic medical record along with a self-report measure.
Outcome measures
| Measure |
Presence of SUD With BCBT
n=55 Participants
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Presence of SUD With TAU
n=61 Participants
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=38 Participants
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
Cognitive Behavioral Therapy: Up to 4 sessions of BCBT (depending on length of stay) will be provided. The first session lasts 1.5 hours and subsequent sessions are 1 hour.
|
Absence of SUD With TAU
n=42 Participants
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Number of Participants With Readmissions
Readmission at Follow-up 1
|
5 Participants
|
8 Participants
|
2 Participants
|
3 Participants
|
|
Number of Participants With Readmissions
Readmission at Follow-up 2
|
7 Participants
|
5 Participants
|
1 Participants
|
2 Participants
|
|
Number of Participants With Readmissions
Readmission at Follow-up 3
|
3 Participants
|
4 Participants
|
1 Participants
|
4 Participants
|
|
Number of Participants With Readmissions
Readmission at Follow-up 4
|
5 Participants
|
6 Participants
|
0 Participants
|
4 Participants
|
|
Number of Participants With Readmissions
Readmission at Follow-up 5
|
6 Participants
|
4 Participants
|
0 Participants
|
3 Participants
|
|
Number of Participants With Readmissions
Readmission at Follow-up 6
|
1 Participants
|
6 Participants
|
3 Participants
|
2 Participants
|
Adverse Events
Presence of SUD With BCBT
Serious events: 23 serious events
Other events: 47 other events
Deaths: 1 deaths
Presence of SUD With TAU
Serious events: 26 serious events
Other events: 50 other events
Deaths: 1 deaths
Absence of SUD With BCBT
Serious events: 8 serious events
Other events: 26 other events
Deaths: 0 deaths
Absence of SUD With TAU
Serious events: 16 serious events
Other events: 31 other events
Deaths: 0 deaths
Serious adverse events
| Measure |
Presence of SUD With BCBT
n=62 participants at risk
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
|
Presence of SUD With TAU
n=65 participants at risk
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=41 participants at risk
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
|
Absence of SUD With TAU
n=45 participants at risk
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
Psychiatric disorders
Psychiatric Inpatient Hospitalization
|
19.4%
12/62 • Number of events 23 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
18.5%
12/65 • Number of events 19 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
14.6%
6/41 • Number of events 6 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
31.1%
14/45 • Number of events 17 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Psychiatric disorders
Change in Mental Health
|
4.8%
3/62 • Number of events 3 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
1.5%
1/65 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
2.4%
1/41 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
2.2%
1/45 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
General disorders
Change in Physical Health/Physical Injury
|
3.2%
2/62 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
3.1%
2/65 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
2.4%
1/41 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
0.00%
0/45 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Psychiatric disorders
Suicide Attempt
|
12.9%
8/62 • Number of events 12 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
15.4%
10/65 • Number of events 15 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
2.4%
1/41 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
8.9%
4/45 • Number of events 4 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
General disorders
Emergency Department Visit
|
12.9%
8/62 • Number of events 10 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
6.2%
4/65 • Number of events 6 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
4.9%
2/41 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
4.4%
2/45 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
General disorders
Medical Hospitalization
|
6.5%
4/62 • Number of events 4 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
7.7%
5/65 • Number of events 6 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
2.4%
1/41 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
4.4%
2/45 • Number of events 4 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Social circumstances
Homelessness
|
1.6%
1/62 • Number of events 1 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
0.00%
0/65 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
0.00%
0/41 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
0.00%
0/45 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
Other adverse events
| Measure |
Presence of SUD With BCBT
n=62 participants at risk
Patients diagnosed with SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of CBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
|
Presence of SUD With TAU
n=65 participants at risk
Patients diagnosed with SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
Absence of SUD With BCBT
n=41 participants at risk
Patients without SUD who are randomly assigned to receive BCBT will participate in all aspects of their prescribed treatment plan (i.e., TAU) and will receive up to 4 sessions of BCBT (depending on length of stay), lasting 1.5 hours for the first session and 1 hour for the remaining sessions.
|
Absence of SUD With TAU
n=45 participants at risk
Patients without SUD who are randomly assigned to receive TAU will participate in all aspects of the prescribed treatment plan given by the inpatient unit.
|
|---|---|---|---|---|
|
General disorders
Change in Physical Health/Physical Injury
|
41.9%
26/62 • Number of events 41 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
35.4%
23/65 • Number of events 34 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
48.8%
20/41 • Number of events 32 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
37.8%
17/45 • Number of events 23 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Psychiatric disorders
Reliable Change in Depression, Stress or Anxiety
|
12.9%
8/62 • Number of events 16 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
9.2%
6/65 • Number of events 7 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
14.6%
6/41 • Number of events 8 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
15.6%
7/45 • Number of events 15 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Psychiatric disorders
Change in Mental Health
|
35.5%
22/62 • Number of events 34 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
46.2%
30/65 • Number of events 47 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
43.9%
18/41 • Number of events 32 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
33.3%
15/45 • Number of events 32 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
Psychiatric disorders
Suicide Attempt
|
11.3%
7/62 • Number of events 7 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
10.8%
7/65 • Number of events 7 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
4.9%
2/41 • Number of events 2 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
8.9%
4/45 • Number of events 6 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
|
General disorders
Emergency Department Visit
|
48.4%
30/62 • Number of events 95 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
36.9%
24/65 • Number of events 66 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
19.5%
8/41 • Number of events 12 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
24.4%
11/45 • Number of events 22 • Adverse events were assessed from the moment participants provided informed consent to the end of the 6-month follow-up period (approximately 7 months, dependent on length of inpatient stay).
|
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place