Trial Outcomes & Findings for Using Open Contest and Neuro-influence Experiment to Develop and Evaluate PrEP Promotion Messages for High Risk Men (NCT NCT04166851)

NCT ID: NCT04166851

Last Updated: 2024-10-22

Results Overview

Questions on willingness to take PrEP. Participants will be asked, "Suppose that PrEP is at least 90% effective in preventing HIV when taken daily. How likely would you be to take PrEP if it were available for free?" with responses ranging from "Extremely unlikely-1," "Somewhat unlikely-2," "Somewhat likely-3," "Extremely likely-4." The mean of the changes between baseline and after participants reviewed the messages was calculated.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

23 participants

Primary outcome timeframe

baseline, 30 days post baseline

Results posted on

2024-10-22

Participant Flow

Participant milestones

Participant milestones
Measure
Open Contest Messages
Participants will view the top PrEP-promotion messages developed via an open contest. PrEP campaign messages developed via open contest: PrEP campaign messages will be developed via an open contest in Baltimore.
Social Marketing Messages
Participants will view the PrEP-promotion messages developed via social marketing. PrEP campaign messages developed via social marketing approach: PrEP campaign messages developed with a traditional social marketing approach.
Overall Study
STARTED
14
9
Overall Study
COMPLETED
14
9
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Some participants didn't answer due to skip pattern in survey

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Open Contest Messages
n=14 Participants
Participants will view the top PrEP-promotion messages developed via an open contest. PrEP campaign messages developed via open contest: PrEP campaign messages will be developed via an open contest in Baltimore.
Social Marketing Messages
n=9 Participants
Participants will view the PrEP-promotion messages developed via social marketing. PrEP campaign messages developed via social marketing approach: PrEP campaign messages developed with a traditional social marketing approach.
Total
n=23 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Age, Categorical
Between 18 and 65 years
13 Participants
n=14 Participants
9 Participants
n=9 Participants
22 Participants
n=23 Participants
Age, Categorical
>=65 years
1 Participants
n=14 Participants
0 Participants
n=9 Participants
1 Participants
n=23 Participants
Age, Continuous
34 years
n=14 Participants
32 years
n=9 Participants
33 years
n=23 Participants
Sex: Female, Male
Female
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Sex: Female, Male
Male
14 Participants
n=14 Participants
9 Participants
n=9 Participants
23 Participants
n=23 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Race (NIH/OMB)
Asian
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Race (NIH/OMB)
Black or African American
13 Participants
n=14 Participants
8 Participants
n=9 Participants
21 Participants
n=23 Participants
Race (NIH/OMB)
White
1 Participants
n=14 Participants
1 Participants
n=9 Participants
2 Participants
n=23 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=14 Participants
0 Participants
n=9 Participants
0 Participants
n=23 Participants
Region of Enrollment
United States
14 Participants
n=14 Participants
9 Participants
n=9 Participants
23 Participants
n=23 Participants
Interntion to use PrEP
3 units on a scale
STANDARD_DEVIATION 1.20 • n=12 Participants • Some participants didn't answer due to skip pattern in survey
3.6 units on a scale
STANDARD_DEVIATION 0.55 • n=5 Participants • Some participants didn't answer due to skip pattern in survey
3.18 units on a scale
STANDARD_DEVIATION 1.07 • n=17 Participants • Some participants didn't answer due to skip pattern in survey

PRIMARY outcome

Timeframe: baseline, 30 days post baseline

Population: Participants who completed the follow-up survey are reported.

Questions on willingness to take PrEP. Participants will be asked, "Suppose that PrEP is at least 90% effective in preventing HIV when taken daily. How likely would you be to take PrEP if it were available for free?" with responses ranging from "Extremely unlikely-1," "Somewhat unlikely-2," "Somewhat likely-3," "Extremely likely-4." The mean of the changes between baseline and after participants reviewed the messages was calculated.

Outcome measures

Outcome measures
Measure
Open Contest Messages
n=5 Participants
Participants will view the top PrEP-promotion messages developed via an open contest. PrEP campaign messages developed via open contest: PrEP campaign messages will be developed via an open contest in Baltimore.
Social Marketing Messages
n=2 Participants
Participants will view the PrEP-promotion messages developed via social marketing. PrEP campaign messages developed via social marketing approach: PrEP campaign messages developed with a traditional social marketing approach.
Change of Willingness to Take PrEP
0 units on a scale
Standard Deviation 0
0.5 units on a scale
Standard Deviation 0.71

Adverse Events

Open Contest Messages

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Social Marketing Messages

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Cui Yang

Rutgers School of Public Health

Phone: 1-732-235-9754

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place