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Effects of Exercise in Patients With Ulcerative Colitis

NCT04143490 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2023-01-05

No results posted yet for this study

Summary

The aim of this study is to investigate the effects of moderate to high intensity exercise on gut function and inflammatory markers in patients with Ulcerative Colitis (UC), and to compare them with individuals of matched age who do not suffer from Inflammatory Bowel Disease. Participants will be asked to complete 60 minutes of continuous cycling at a moderate to high intensity followed by a three hour recovery period. Gastrointestinal function will be measured using a non-invasive breath test. Blood samples will be collected at multiple time-points during the visit and these samples will be measured for markers of immune function and intestinal integrity.

Conditions

Interventions

OTHER

Exercise

60 minutes of continuous exercise at 65% VO2peak and drink ingestion

Sponsors & Collaborators

  • University of Manchester

    collaborator OTHER

  • Manchester Metropolitan University

    lead OTHER

Principal Investigators

  • Gethin H Evans, PhD · Manchester Metropolitan University

  • Adora MW Yau, PhD · Manchester Metropolitan University

  • John McLaughlin, Prof. · University of Manchester

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-04
Primary Completion
2024-09-30
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04143490 on ClinicalTrials.gov