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ICONIC: Improving Outcomes Through Collaboration in OsteosarComa

NCT04132895 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2024-08-02

No results posted yet for this study

Summary

There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because there is no good understanding of the biology of osteosarcoma, but also trials have only included subgroups of patients. The more that is understood about how and why osteosarcoma arises and grows the better clinicians will be able to decide what treatments are most likely to work best.

The purpose of this project is to collect high quality clinical data about patients of all ages with osteosarcoma, such as information about the size of the disease, how it was diagnosed and where it is at diagnosis, what treatments were given and how the disease responded the treatments.

Blood and tissue samples will also be collected for analysis in research laboratories. By looking at the results of the laboratory findings and the clinical data together, the questions will start to be answered about why osteosarcomas arise and grow, what makes it spread, and why some patients respond to treatment better than others. As time goes on, this information is planned to be used to develop clinical trials of new treatments.

Alongside this, the aim is to find out more about how osteosarcoma and its treatments affect the lives of those living with this disease. This information will help provide the most appropriate care and support that will meet the needs of each patient.

Ultimately, the aim is to improve the care and treatment of osteosarcoma patients so that they may live longer and better lives.

Conditions

Interventions

OTHER

observational only, no interventions are prescribed in protocol.

* Treatment will be given as per usual standard of care. * No treatments are specified by this protocol.

Sponsors & Collaborators

  • Bone Cancer Research Trust

    collaborator UNKNOWN

  • University College, London

    lead OTHER

Principal Investigators

  • Sandra Strauss, MD · University College Hospitals London

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-10-25
Primary Completion
2025-01-31
Completion
2027-01-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04132895 on ClinicalTrials.gov