A Trial of Camrelizumab in Combination With Nab-paclitaxel and Famitinib as a First Line Treatment in Patients With Unresectable Locally Advanced or Metastatic Immunomodulatory Triple Negative Breast Cancer(FUTURE-C-PLUS)
NCT04129996 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 46
Last updated 2022-01-11
Summary
The study is being conducted to evaluate the efficacy, safety of camrelizumab in combination with nab-paclitaxel and famitinib in Patients with unresectable locally advanced or metastatic immunomodulatory triple negative breast Cancer..
Conditions
- Triple-Negative Breast Cancer
Interventions
- DRUG
-
camrelizumab in combination with nab-paclitaxel and famitinib
camrelizumab in combination with nab-paclitaxel and famitinib for triple negative breast cancer
Sponsors & Collaborators
-
Fudan University
lead OTHER
Principal Investigators
-
zhimin shao, MD,PHD · Fudan University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-01
- Primary Completion
- 2022-09-01
- Completion
- 2022-09-01
Countries
- China
Study Locations
More Related Trials
-
A Multi-center, Randomized, Open-label, Phase III Study Comparing PD-1 Inhibitor Combined With Antivascular Therapy and Anthracycline/Taxane-based Adjuvant Chemotherapy Versus Anthracycline/Taxane-based Adjuvant Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer
NCT05862064 ·Status: RECRUITING ·Phase: PHASE3
-
Camrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer
NCT07161791 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Fluzoparib in Combination With Chidamide or Camrelizumab for HRD Positive HER2 Negative Advanced Breast Cancer
NCT05085626 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Dose-dense EC Followed by ABX With PD-1 for Triple Negative Breast Cancer Patients
NCT04418154 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
An Umbrella Trial Based on Molecular Pathway for Patients With Metastatic TNBC.
NCT04395989 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Induction of Cisplatin/Nab-paclitaxel/Pembrolizumab Followed by Olaparib/Pembrolizumab Maintenance in mTNBC Patients
NCT05174832 ·Status: UNKNOWN ·Phase: PHASE2
-
JAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC
NCT06731153 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
QL1706 Plus Chemotherapy +/- Bevacizumab in 1L Treatment of R/mTNBC
NCT06786026 ·Status: RECRUITING ·Phase: PHASE2
-
Camrelizumab in Combination With Chemotherapy as Neoadjuvant Treatment in Patients With Early or Locally Advanced Triple-negative Breast Cancer
NCT07107217 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Phase 3 Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.
NCT04335006 ·Status: TERMINATED ·Phase: PHASE3
-
Study Of Capecitabine Combined With Camrelizumab For Non-pCR TNBC With TLS After Neoadjuvant Chemoterapy
NCT06313463 ·Status: RECRUITING ·Phase: PHASE3
-
Study Comparing Paclitaxel Plus Carboplatin Versus Anthracyclines Followed by Docetaxel as Adjuvant Chemotherapy for Triple Negative Breast Cancer (PATTERN)
NCT04031703 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of PM8002 Plus Nab-paclitaxel as First Line Therapy for TNBC
NCT05918133 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
SBRT, Chemotherapy, and AK104 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC)
NCT06401005 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of QL1706 Combined With Short-Cycle Anthracyclines or Taxanes for the Treatment of Early-Stage TNBC
NCT07178171 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Camrelizumab in Combination With Chemotherapy Regimen Comparative Chemotherapy Regimen for Metastatic Triple-negative Breast Cancer
NCT05134194 ·Status: TERMINATED ·Phase: PHASE3
-
Camrelizumab in Combination With PLD and Losartan in Patients With TNBC Who Have Received ≦ 1 Line of Chemotherapy
NCT05097248 ·Status: UNKNOWN ·Phase: PHASE2
-
Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy
NCT04437160 ·Status: RECRUITING ·Phase: PHASE2
-
To Evaluate the Efficacy of Toripalimab Combined With Chemotherapy After HIFU Induction in the Treatment of Early Triple-negative Breast Cancer
NCT05491694 ·Status: UNKNOWN ·Phase: PHASE2
-
Reverse Triple Negative Immune Resistant Breast Cancer
NCT05076682 ·Status: RECRUITING ·Phase: PHASE2
-
Iparomlimab and Tuvonralimab (QL1706) in Patients With HR-positive, HER2-negative Advanced Breast Cancer
NCT07180160 ·Status: RECRUITING ·Phase: PHASE2
-
QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer
NCT06404736 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Dual Anti-HER2 Therapy (Lapatinib and Trastuzumab) Plus Chemotherapy in HER2-positive MBC
NCT04001634 ·Status: COMPLETED
-
Albumin-Bound Paclitaxel Followed by Epirubicin in Combination With Cyclophosphamide in Triple Negative Breast Cancer
NCT03799679 ·Status: UNKNOWN ·Phase: PHASE4
-
SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC
NCT06627712 ·Status: RECRUITING ·Phase: PHASE3