Trial Outcomes & Findings for Central Pain Syndrome in Survivors of Head and Neck Cancer (NCT NCT04128267)

NCT ID: NCT04128267

Last Updated: 2022-09-19

Results Overview

MRI scan of brain to measure response to stimulated pressure to thumbnail

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

32 participants

Primary outcome timeframe

Approximately 8 weeks

Results posted on

2022-09-19

Participant Flow

This study enrolled participants at Vanderbilt University Medical Center from November 4, 2019 to July 21, 2022. The study stopped early due to low accrual and technical issues with equipment.

Participant milestones

Participant milestones
Measure
Response to Pain
Brain's response to pain using magnetic resonance imaging (MRI) IPC-1000: Delivers pressure to thumbnail for five seconds at a time Magnetic resonance imaging: Scan of brain using Magnetic resonance imaging Correlative Studies: Administration of questionnaires via computer
Overall Study
STARTED
32
Overall Study
COMPLETED
17
Overall Study
NOT COMPLETED
15

Reasons for withdrawal

Reasons for withdrawal
Measure
Response to Pain
Brain's response to pain using magnetic resonance imaging (MRI) IPC-1000: Delivers pressure to thumbnail for five seconds at a time Magnetic resonance imaging: Scan of brain using Magnetic resonance imaging Correlative Studies: Administration of questionnaires via computer
Overall Study
Withdrawal by Subject
6
Overall Study
Death
2
Overall Study
Disease progression
1
Overall Study
Participant had other medical issues
4
Overall Study
Participant failed to respond to multiple attempts to contact
2

Baseline Characteristics

Central Pain Syndrome in Survivors of Head and Neck Cancer

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Response to Pain
n=32 Participants
Brain's response to pain using magnetic resonance imaging (MRI) IPC-1000: Delivers pressure to thumbnail for five seconds at a time Magnetic resonance imaging: Scan of brain using Magnetic resonance imaging Correlative Studies: Administration of questionnaires via computer
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
26 Participants
n=99 Participants
Age, Categorical
>=65 years
6 Participants
n=99 Participants
Sex: Female, Male
Female
7 Participants
n=99 Participants
Sex: Female, Male
Male
25 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
32 Participants
n=99 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
Race (NIH/OMB)
Asian
0 Participants
n=99 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=99 Participants
Race (NIH/OMB)
White
31 Participants
n=99 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
Region of Enrollment
United States
32 participants
n=99 Participants

PRIMARY outcome

Timeframe: Approximately 8 weeks

Population: Data were not collected due to the technical issues.

MRI scan of brain to measure response to stimulated pressure to thumbnail

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Approximately 8 weeks

Population: Data were not collected due to the technical issues.

MRI scan of brain to measure response to stimulated pressure to thumbnail

Outcome measures

Outcome data not reported

Adverse Events

Response to Pain

Serious events: 0 serious events
Other events: 0 other events
Deaths: 3 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Teresa Melton

Vanderbilt-Ingram Cancer Center

Phone: (615) 936-7423

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place