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Exparel Injection Effect on Postoperative Opioid Usage

NCT04085913 · Status: ENROLLING_BY_INVITATION · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2024-07-29

No results posted yet for this study

Summary

The question proposed by this study, is one of patient outcomes. Does intraoperative injection of Exparel decrease postoperative use of opioid pain medications in patients undergoing thyroid and parathyroid surgery? The trial seeks to assess the effect that Exparel has on postoperative pain control.

Conditions

  • Thyroid
  • Parathyroid Adenoma

Interventions

DRUG

Lidocaine Epinephrine

Preincision injection, as is current practice

DRUG

Bupivacaine Hydrochloride-EPINEPHrine

Preincision injection

DRUG

Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine

Preincison injection of lidocaine and epinephrine and a postincision injection of Exparel

Sponsors & Collaborators

  • University of Missouri-Columbia

    lead OTHER

Principal Investigators

  • Tabitha Galloway, MD · University of Missouri Department of Otolaryngology-Head and Neck Surgery

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-30
Primary Completion
2024-06-06
Completion
2025-07-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04085913 on ClinicalTrials.gov