Trial Outcomes & Findings for Chronic HBV Management for Asian American (NCT NCT04082338)

NCT ID: NCT04082338

Last Updated: 2023-06-22

Results Overview

percentage of subjects, who visited doctor's office for HBV at 12-month and 18-month Follow-Up

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

382 participants

Primary outcome timeframe

12 months, 18 months

Results posted on

2023-06-22

Participant Flow

Participant milestones

Participant milestones
Measure
VPN Toolkit+TM
The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application) format. VPN: The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application). The system includes education modules on HBV management, CHB patient success stories and virtual patient navigation clinical support for overcoming barriers. In addition to the VPN, each participant will receive 5 text messages; one message once a week for 5 weeks on HBV management for every 6 months in the 18-month study period. TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Text Messages
Receive TM respectively once a week for 5 weeks for every 6 months in the 18-month study period TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Overall Study Baseline
STARTED
191
191
Overall Study Baseline
COMPLETED
191
191
Overall Study Baseline
NOT COMPLETED
0
0
12-month Follow-up
STARTED
191
191
12-month Follow-up
COMPLETED
186
186
12-month Follow-up
NOT COMPLETED
5
5
18-month Follow-up
STARTED
186
186
18-month Follow-up
COMPLETED
181
184
18-month Follow-up
NOT COMPLETED
5
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Chronic HBV Management for Asian American

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
VPN Toolkit+TM
n=191 Participants
The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application) format. VPN: The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application). The system includes education modules on HBV management, CHB patient success stories and virtual patient navigation clinical support for overcoming barriers. In addition to the VPN, each participant will receive 5 text messages; one message once a week for 5 weeks on HBV management for every 6 months in the 18-month study period. TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Text Messages
n=191 Participants
Receive TM respectively once a week for 5 weeks for every 6 months in the 18-month study period TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Total
n=382 Participants
Total of all reporting groups
Age, Continuous
53.29 Years
STANDARD_DEVIATION 0.91 • n=99 Participants
53.18 Years
STANDARD_DEVIATION 1.04 • n=107 Participants
53.23 Years
STANDARD_DEVIATION 1.38 • n=206 Participants
Sex: Female, Male
Female
99 Participants
n=99 Participants
99 Participants
n=107 Participants
198 Participants
n=206 Participants
Sex: Female, Male
Male
92 Participants
n=99 Participants
92 Participants
n=107 Participants
184 Participants
n=206 Participants
Race/Ethnicity, Customized
Chinese
148 Participants
n=99 Participants
150 Participants
n=107 Participants
298 Participants
n=206 Participants
Race/Ethnicity, Customized
Vietnamese
43 Participants
n=99 Participants
41 Participants
n=107 Participants
84 Participants
n=206 Participants
Born in the US
Yes
1 Participants
n=99 Participants
4 Participants
n=107 Participants
5 Participants
n=206 Participants
Born in the US
No
190 Participants
n=99 Participants
187 Participants
n=107 Participants
377 Participants
n=206 Participants

PRIMARY outcome

Timeframe: 12 months, 18 months

Population: There are 3 cases (1 intervention, 2 control cases) missing information on doctor's visit at the 12-month follow-up assessment point.

percentage of subjects, who visited doctor's office for HBV at 12-month and 18-month Follow-Up

Outcome measures

Outcome measures
Measure
VPN Toolkit+TM
n=185 Participants
The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application) format. VPN: The intervention will be delivered through virtual patient navigation (VPN) toolkit system (a web/mobile application). The system includes education modules on HBV management, CHB patient success stories and virtual patient navigation clinical support for overcoming barriers. In addition to the VPN, each participant will receive 5 text messages; one message once a week for 5 weeks on HBV management for every 6 months in the 18-month study period. TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Text Messages
n=184 Participants
Receive TM respectively once a week for 5 weeks for every 6 months in the 18-month study period TM: Receive TM on HBV management respectively once a week for 5 weeks for every 6 months in the 18-month study period.
Adherence to Recommended HBV Monitoring: Doctor's Visits
Doctor's Visit by 12-month follow-up
159 Participants
100 Participants
Adherence to Recommended HBV Monitoring: Doctor's Visits
Doctor's Visit by 18-month follow-up
170 Participants
147 Participants

Adverse Events

VPN Toolkit+TM

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Text Messages

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Grace X. Ma

Center for Asian Health, Lewis Katz School of Medicine, Temple University

Phone: 215-707-6493

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place