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PLATO - Medication Adherence in Transplant Recipients

NCT04078750 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 99

Last updated 2024-05-13

No results posted yet for this study

Summary

Non-adherence with immunosuppressant drugs is a major reason for premature kidney transplant failure. Currently, patient education and compliance aids (e.g bubble packing) are commonly used to assist patients. This is a study involving patients expected to undergo a kidney transplant within 6 months. One group will undergo a one-month formal assessment of adherence before transplantation using mock immunosuppressant medication. Standardized surveys will also be administered to assess risk factors for non-adherence. A plan will be developed for use after the transplant. The other group will undergo usual care. Kidney function and rejection rates will be compared between two groups.

Conditions

  • Kidney Disease, Chronic
  • Medication Adherence
  • Renal Disease
  • Kidney Rejection Transplant

Interventions

BEHAVIORAL

Tailored medication adherence plan

Comparison of mean daily medication adherence between intervention and control groups over 3 months, as measured by MEMS caps.

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Marianna Leung, Pharm D · St. Paul's Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-10
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04078750 on ClinicalTrials.gov