Trial Outcomes & Findings for External Fixation Versus Splinting of Acute Calcaneus Fractures (NCT NCT04063657)

NCT ID: NCT04063657

Last Updated: 2022-02-09

Results Overview

Incidence of infection, dehiscence and need for soft tissue coverage

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

1 participants

Primary outcome timeframe

Assessed at 12 weeks after surgery

Results posted on

2022-02-09

Participant Flow

Participant milestones

Participant milestones
Measure
External Fixation
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in external fixator until the patient is deemed clinically appropriate for definitive surgical fixation. External fixator: Patients will be placed in an external fixator followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Splinting
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in a short leg splint until the patient is deemed clinically appropriate for definitive surgical fixation. Splinting: Patients will be placed in a short leg splint followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Overall Study
STARTED
1
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
1
0

Reasons for withdrawal

Reasons for withdrawal
Measure
External Fixation
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in external fixator until the patient is deemed clinically appropriate for definitive surgical fixation. External fixator: Patients will be placed in an external fixator followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Splinting
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in a short leg splint until the patient is deemed clinically appropriate for definitive surgical fixation. Splinting: Patients will be placed in a short leg splint followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Overall Study
Lost to Follow-up
1
0

Baseline Characteristics

External Fixation Versus Splinting of Acute Calcaneus Fractures

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
External Fixation
n=1 Participants
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in external fixator until the patient is deemed clinically appropriate for definitive surgical fixation. External fixator: Patients will be placed in an external fixator followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Splinting
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in a short leg splint until the patient is deemed clinically appropriate for definitive surgical fixation. Splinting: Patients will be placed in a short leg splint followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Total
n=1 Participants
Total of all reporting groups
Age, Continuous
50 years
n=99 Participants
50 years
n=206 Participants
Sex: Female, Male
Female
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Sex: Female, Male
Male
1 Participants
n=99 Participants
1 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
1 Participants
n=99 Participants
1 Participants
n=206 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Asian
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=99 Participants
1 Participants
n=206 Participants
Race (NIH/OMB)
White
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=99 Participants
0 Participants
n=206 Participants
Region of Enrollment
United States
1 participants
n=99 Participants
1 participants
n=206 Participants

PRIMARY outcome

Timeframe: Within 2 weeks from injury

Population: Study stopped prematurely due to poor recruitment. Only 1 subject was enrolled.

Duration of time from injury to definitive surgery

Outcome measures

Outcome measures
Measure
External Fixation
n=1 Participants
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in external fixator until the patient is deemed clinically appropriate for definitive surgical fixation. External fixator: Patients will be placed in an external fixator followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Splinting
Adults diagnosed with an acute (\<2 days from injury) calcaneal fracture recommended for operative treatment will be placed in a short leg splint until the patient is deemed clinically appropriate for definitive surgical fixation. Splinting: Patients will be placed in a short leg splint followed by open versus closed surgical stabilization of their calcaneus fracture when their soft tissue is appropriate for surgery.
Time to Definitive Surgery
3 days

PRIMARY outcome

Timeframe: Assessed at 2 weeks after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Assessed at 6 weeks after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Assessed at 12 weeks after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Assessed at 6 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Assessed at 12 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Assessed at 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Incidence of infection, dehiscence and need for soft tissue coverage

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Plain xrays at 6 weeks, 12 weeks, 6 months, 1 year, and 2 years after surgery. CT scan at 1 year.

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Assessment of fracture healing

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Bohler's angle

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Calcaneal height

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Angle of Gissan

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Calcaneal width

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Calcaneal length

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery.

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Assess Visual Analogue pain score(VAS). This will be a patient reported measure from 0-10, minimum score of 0 (no pain), maximum score of 10 (most pain).

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Revised foot function index questionnaire (FFI-R) will assess patient pain, stiffness, activity, difficulties with ambulation, and social issues. The score is tabulated from 34 questions answered 1-5 (1= none of the time, 5= All of the time, scale 34-170). Higher scores indicate worse outcomes.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Foot and Ankle Ability measure activities of daily living (FAAM ADL) is a 21-item activities assessing the patient's functionality related to their activities of daily living. The response to each item is scored from 4 to 0, with 4 being ''no difficulty'' and 0 being ''unable to do." Scale 0-84. Higher scores indicate a more favorable functional level.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Assessed at 2, 6, & 12 weeks, and 6, 12, & 24 months after surgery

Population: Study stopped prematurely due to poor recruitment. Only 1 participant was enrolled. Participant did not attend follow up visit where this data would have been collected.

Foot and Ankle Ability measure activities of daily living (FAAM Sport) is a 8-item questionnaire assess the patient's ability to participate in athletic activities. The response to each item is scored from 4 to 0, with 4 being ''no difficulty'' and 0 being ''unable to do." Scale 0-32. Higher scores indicate a more favorable functional level.

Outcome measures

Outcome data not reported

Adverse Events

External Fixation

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Splinting

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Christopher Kreulen

University of California, Davis

Phone: (916) 734-6805

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place