QUILT-3.061: CD19 t-haNK in Subjects With Diffuse Large B-Cell Lymphoma
NCT04052061 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2025-02-21
Summary
Phase 1 study to assess the safety, preliminary efficacy of CD19 t-haNK and to determine the maximal tolerated dose and designate the recommended phase 2 dose in subjects with diffuse large B-cell lymphoma (DLBCL).
Conditions
- Diffuse Large B Cell Lymphoma
- Large-cell Lymphoma
- Lymphoma, B-Cell
- Lymphoma
Interventions
- BIOLOGICAL
-
CD19 t-haNK
CD19 t-haNK Suspension for Infusion
Sponsors & Collaborators
-
ImmunityBio, Inc.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-16
- Primary Completion
- 2021-09-18
- Completion
- 2022-08-19
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
NCT02957019 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Memory Enriched T Cells Following Stem Cell Transplant in Treating Patients With Recurrent B-Cell Non-Hodgkin Lymphoma
NCT02051257 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
NCT05421663 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy
NCT05075603 ·Status: COMPLETED ·Phase: PHASE1
-
CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL
NCT00586391 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of BGB-30813 Alone or in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors
NCT05904496 ·Status: TERMINATED ·Phase: PHASE1
-
Study of Fc-Optimized Anti-CD19 Antibody (MOR00208) to Treat Non-Hodgkin's Lymphoma (NHL)
NCT01685008 ·Status: COMPLETED ·Phase: PHASE2
-
A First-in-Human, Phase 1 Dose-Escalation and Cohort Expansion Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BJ-005 in Patients With Advanced Solid Tumor or Lymphoma
NCT05115292 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase 1/2 Study of CT120 in Patient With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
NCT05091541 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma and Follicular Lymphoma
NCT02031419 ·Status: TERMINATED ·Phase: PHASE1
-
Treatment of Non-Hodgkin Lymphoma With CD19-TriCAR-T/SILK Cell Therapy
NCT03790891 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Intensive Chemotherapy and Rituximab in the Treatment of Burkitt Lymphoma
NCT00126191 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase I Study to Evaluate Safety, Tolerability in Adults With Lymphoma
NCT00538096 ·Status: WITHDRAWN ·Phase: PHASE1
-
QUILT-3.002: N-803 in Patients With Relapse/Refractory iNHL in Conjunction With Rituximab
NCT02384954 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Pembrolizumab for Patients With PD-L1 Diffuse Large B Cell Lymphoma (DLBCL)
NCT03990961 ·Status: TERMINATED ·Phase: PHASE2
-
Quality of Life of Adults With Diffuse Large B-cell Lymphoma Treated With Tisagenlecleucel
NCT05199961 ·Status: TERMINATED ·Phase: NA
-
Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL
NCT06104592 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of RD14-01 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
NCT05444322 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
A Study of bbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL)
NCT05169489 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of GNC-038, a Tetra-specific Antibody, in Participants With R/R Diffuse Large B-cell Lymphoma (DLBCL)
NCT05192486 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Recurrent or Refractory Lymphoma
NCT00007956 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated High- or High-Intermediate-Risk Diffuse Large B-Cell Lymphoma
NCT01539174 ·Status: WITHDRAWN ·Phase: PHASE2
-
CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
NCT06026319 ·Status: RECRUITING ·Phase: PHASE1
-
Retrospective Analysis of Rituximab-containing Immunochemotherapy for Burkitt's or Burkitt-like Lymphoma in Adults
NCT01809600 ·Status: COMPLETED
-
A Phase 1b/2 Safety and Tolerability Study of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies
NCT02205333 ·Status: TERMINATED ·Phase: PHASE1/PHASE2