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Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)

NCT04041622 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56000

Last updated 2025-05-25

No results posted yet for this study

Summary

In this study, all citizen of Nord-Trøndelag County, Norway, above 20 years of age are invited to participate in a population-based health study, the HUNT study. Blood samples are drawn from the participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will be verified through endoscopic assessment and biopsies from the small intestinal mucosa. The aims of the study are 1) to establish the population-based prevalence of celiac disease; 2) to assess the consequences of the disease from patient reported outcomes, symptoms, deficiencies, and co-morbidity; 3) to study possible risk factors and environmental triggering events; 4) to identify genetic predictors and gene-environmental interactions.

Conditions

Interventions

DIAGNOSTIC_TEST

Endoscopy and biopsy

Participants with a positive celiac serology are assessed by endoscopy and duodenal biopsy

Sponsors & Collaborators

  • University of Oslo

    collaborator OTHER

  • Oslo University Hospital

    collaborator OTHER

  • Helse Nord-Trøndelag HF

    collaborator OTHER

  • University of Groningen

    collaborator OTHER

  • Karolinska Institutet

    collaborator OTHER

  • Norwegian University of Science and Technology

    lead OTHER

Principal Investigators

  • Eivind Ness-Jensen, md phd · NTNU, Norwegian University of Science and Technology

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-06-17
Primary Completion
2024-07-01
Completion
2024-07-01

Countries

  • Norway

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04041622 on ClinicalTrials.gov