Combination Camrelizumab (SHR-1210) and Apatinib for Downstaging/Bridging of HCC Before Liver Transplant
NCT04035876 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2019-07-29
Summary
To assess the primary effects and safety of camrelizumab (SHR-1210) plus apatinib for downstaging/bridging of HCC before liver transplantation.
Conditions
- Hepatocellular Carcinoma
- Liver Transplant
Interventions
- DRUG
-
Camrelizumab plus apatinib
Camrelizumab 200mg q2w iv and apatinib 250mg qd po.
Sponsors & Collaborators
-
Shulan (Hangzhou) Hospital
collaborator OTHER -
West China Hospital
collaborator OTHER -
Huashan Hospital
collaborator OTHER -
Third Affiliated Hospital, Sun Yat-Sen University
collaborator OTHER -
The First Affiliated Hospital of Zhengzhou University
collaborator OTHER -
The First Hospital of Jilin University
collaborator OTHER -
Tianjin First Central Hospital
collaborator OTHER -
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
collaborator OTHER -
Zhejiang University
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-16
- Primary Completion
- 2021-12-31
- Completion
- 2021-12-31
Countries
- China
Study Locations
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