Impact of Oral Glucose Tolerance Test on Extent of Hemoglobin Glycation

NCT04018430 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2019-07-12

No results posted yet for this study

Summary

The glycation extent of human hemoglobin is under control of the Maillard reaction, a chemical interaction between an amino acide and a reducing sugar. About 5% ( 31.1 mmol/mol) of hemoglobin molecules secluded in a red blood cell are glycated; excessive values \> 6.5% point to prediabetes or overt diabetes mellitus. To ascertain the diagnosis doctors prescribe oral glucose tolerance upon which glucose concentrations in blood increase - how much HbA1c reacts under these circumstances is ill known.

Conditions

  • Blood Glucose, High
  • Oral Hypoglycaemic Overdose

Sponsors & Collaborators

  • Labormedizinisches Zentrum Dr. Risch

    collaborator INDUSTRY
  • Urs E. Nydegger

    lead INDUSTRY

Principal Investigators

  • Urs Nydegger, MD · Labormedizinisches Zentrum Dr. Risch

Eligibility

Min Age
5 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-01
Primary Completion
2020-09-30
Completion
2021-09-30

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04018430 on ClinicalTrials.gov