A Study of MT-0169 in Participants With Relapsed or Refractory Multiple Myeloma
NCT04017130 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2024-01-17
Summary
This will be a Phase 1 Open-Label, dose escalation of MT-0169 (an Engineered toxin body (ETB) in patients with relapsed or refractory multiple myeloma. MT-0169 is an investigational drug that recognizes and binds to the CD38 receptor, which may be found on the surface of multiple myeloma cancer cells. It delivers a dose of a modified toxin that kills these cells.
Conditions
- Relapsed and/or Refractory Multiple Myeloma
Interventions
- DRUG
-
MT-0169
MT-0169 intravenous infusion.
Sponsors & Collaborators
-
Molecular Templates, Inc.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-02-05
- Primary Completion
- 2023-12-13
- Completion
- 2023-12-13
- FDA Drug
- Yes
Countries
- United States
Study Locations
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