Mechanisms of LPRF Action in the Promotion of Wound Healing and Tissue Regeneration
NCT03992638 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2023-02-15
Summary
This study evaluates the clinical and biological effects of leucocyte and platelet-rich fibrin (L-PRF) on intraoral wound healing.
Conditions
- Gingival Recession
Interventions
- PROCEDURE
-
leucocyte and platelet-rich fibrin (L-PRF) in combination with CAF
Completing root coverage by coronally advanced flap technique in combination with L-PRF.
- PROCEDURE
-
CAF
Completing root coverage by coronally advanced flap technique alone
Sponsors & Collaborators
-
The University of Hong Kong
collaborator OTHER -
The European Research Group on Periodontology (ERGOPerio)
lead NETWORK
Principal Investigators
-
Maurizio Tonetti, PhD MMSc · The European Research Group on Periodontology (ERGOPerio)
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-09-01
- Primary Completion
- 2021-12-30
- Completion
- 2022-12-31
Countries
- Hong Kong
Study Locations
More Related Trials
-
Platelet Rich Fibrin in Soft Tissue Healing After Implant Uncovering
NCT05375357 ·Status: COMPLETED ·Phase: NA
-
PRF for Accelerating Palatal Healing
NCT02712242 ·Status: COMPLETED ·Phase: NA
-
Clinical Evaluation of Gingival Biotype Changes Using a Coronally Advanced Flap (CAF) in Combination with Leucocyte and Platelet- Rich Fibrin (L-PRF) Membranes of Different Thickness for the Treatment of RT1 Gingival Recession: a Randomized Controlled Clinical Trial.
NCT06701799 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
NCT05866965 ·Status: COMPLETED ·Phase: NA
-
Effect of Leucocyte- and Platelet-Rich Fibrin on Palatal Wound Healing After Free Gingival Graft Harvesting
NCT06777069 ·Status: COMPLETED ·Phase: NA
-
Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)
NCT04978324 ·Status: WITHDRAWN ·Phase: PHASE3
-
CGF and PRF in the Gingival Recessions Treatment
NCT04261634 ·Status: COMPLETED ·Phase: NA
-
Guided Tissue Regeneration in Healing of Through and Through Periapical Lesion
NCT04391725 ·Status: UNKNOWN ·Phase: NA
-
Growth Factors Release of PRF and PRGF
NCT02447510 ·Status: COMPLETED ·Phase: PHASE3
-
Platelet Rich Fibrin in the Treatment of Palatal Wounds
NCT02438046 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of the Entire Papilla Preservation Technique With and Without the Use of L-PRF as a Regenerative Material for the Treatment of Infrabony Defects
NCT06694168 ·Status: RECRUITING ·Phase: NA
-
Platelet-Rich Fibrin in Intraoral Soft Tissue Regeneration
NCT04022720 ·Status: WITHDRAWN ·Phase: NA
-
Effect of I-PRF After Gingivectomy
NCT07174934 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Clinical Impact of L-PRF, H-PRF or the Use of Surgical Stent on Palatal Donor Site Healing.
NCT04758702 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Monolayer Versus Multilayer Leucocyte-Platelet Rich Fibrin (L-PRF) in Interdental Papillary Reconstruction
NCT04091802 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Platelet Rich Plasma in Wound Healing
NCT02831374 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular Surgery
NCT05847647 ·Status: COMPLETED ·Phase: NA
-
The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects
NCT04576468 ·Status: COMPLETED ·Phase: NA
-
Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study.
NCT07257328 ·Status: COMPLETED ·Phase: NA
-
L-PRF Versus Connective Tissue Graft Associated to Coronally Advanced Flap in Gingival Recession Treatment
NCT04165044 ·Status: COMPLETED ·Phase: NA
-
The Use of PRF in the Management of Soft Tissue Healing
NCT04212767 ·Status: COMPLETED ·Phase: NA
-
Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects
NCT02283554 ·Status: COMPLETED ·Phase: PHASE2
-
Topical Application of PRF Before Radiation Therapy
NCT06406530 ·Status: RECRUITING ·Phase: NA
-
Comparing the Position of Collagen Membrane During Immediate Implant Placement
NCT04224935 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Platelet Rich Fibrin Matrix as Regenerative Material in Intraosseous Defects
NCT03616925 ·Status: COMPLETED ·Phase: PHASE3