PDR001 + Panobinostat for Melanoma and NSCLC
NCT03982134 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2019-10-04
Summary
The purpose of this research study is to find the dose of the study drug PDR001 that, when given in combination with the drug Panobinostat, results in the best outcomes for metastatic melanoma and non-small cell lung cancer (NSCLC)
Conditions
- Melanoma
- Non Small Cell Lung Cancer
Interventions
- DRUG
-
PDR001
PDR001 is a humanized IgG4 antibody
- DRUG
-
Panobinostat
Panobinostat is a Histone deacetylase inhibitor (HDACi).
Sponsors & Collaborators
- collaborator INDUSTRY
-
Muhammad Furqan
lead OTHER
Principal Investigators
-
Muhammad Furqan, MD · University of Iowa
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-09-30
- Primary Completion
- 2021-05-01
- Completion
- 2022-05-01
- FDA Drug
- Yes
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