Functional MRI in Predicting Response to Chemotherapy
NCT03969524 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2020-12-29
Summary
• Address the accuracy of functional MRI techniques to predict response to neoadjuvant chemotherapy given to local advanced breast cancer patients with correlation with pathology thus allowing early chemotherapy regimen modification to increase number of patients achieving pathological complete response or save patients from toxic effects of ineffective chemotherapy.
Conditions
- Breast Cancer Patients
Interventions
- DEVICE
-
MRI
Patients will undergo magnetic resonance imaging (MRI) at baseline (T0) (before NAC) and after the 2nd cycle of neoadjuvant chemotherapy(T2). Histopathological examination (gold standard) of the surgical specimen will be done for each patient and Compared to the results of MRI.
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Osama HA El-Sayed, Professor · Assiut University
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-06-15
- Primary Completion
- 2023-06-15
- Completion
- 2023-12-30
Countries
- Egypt
Study Locations
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