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Macroscopic and Molecular Changes in Knee Muscular-tendon Unit in Response to Acute Resistant Load

NCT03950596 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2019-05-15

No results posted yet for this study

Summary

The aim of this study is to determine the influence of acute resistance exercises on anatomical and biological changes in the quadriceps muscle and tendons of the knee

Conditions

  • Quadriceps Muscle

Interventions

OTHER

Acute resistant load exercises

Leg bench and leg press acute resistant load exercises Leg-bench and leg-press acute resistant load exercises

BEHAVIORAL

Background Questionnaire

Background questionnaire will be filled out by participants

OTHER

Pain Questionnaire

Pain questionnaire regarding pain in the knee during previous 3 months

GENETIC

DNA and RNA test

DNA and RNA tests will be sent to a genetic laboratory for analysis

DIAGNOSTIC_TEST

Ultrasound

Ultrasound of the knee joint and the quadriceps muscle and the pica tendon

DIAGNOSTIC_TEST

Percutaneous Needle Core Biopsy

Core Biopsy will be taken from the quadriceps femoris muscle

Sponsors & Collaborators

  • Hillel Yaffe Medical Center

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-05-31
Primary Completion
2020-05-31
Completion
2020-05-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03950596 on ClinicalTrials.gov