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Aspirin Resistance in OSA Patients

NCT03930875 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 63

Last updated 2019-04-29

No results posted yet for this study

Summary

Obstructive Sleep Apnea (OSA) patients are at increased risk of major cardiovascular events, so many patients take aspirin for prevention. Poor responsiveness to aspirin is a major clinical concern because it can potentially worsen the prognosis of OSA patients. However, continuous positive airway pressure (CPAP) therapy that is considered standard of care for OSA treatment may potentially lead to improvement in responsiveness to aspirin. This study will determine whether CPAP therapy decreases patients' aspirin resistance in OSA patients with a new diagnosis or existing moderate to severe OSA who are treated with CPAP and take aspirin for prevention.

Conditions

Interventions

OTHER

Aspirin Resistance testing

Aspirin resistance will be measured using platelet aggregometry (VerifyNow assay)

Sponsors & Collaborators

  • Accriva Diagnostics

    collaborator INDUSTRY

  • Danbury Hospital

    lead OTHER

Principal Investigators

  • Jose L Mendez · Nuvance Health

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-12-12
Primary Completion
2018-09-07
Completion
2018-09-07

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03930875 on ClinicalTrials.gov