Korea Osimertinib Real World Evidence Study to Assess Safety and Efficacy - PLUS
NCT03918304 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 923
Last updated 2025-10-23
Summary
This is a local, prospective, non-interventional, regulatory postmarketing surveillance study. The objectives of this study are to assess the safety and efficacy of single agent Tagrisso (Osimertinib, hereinafter "the study drug") in a real world setting according to the approved label in Korea.
Conditions
- Carcinoma, Non-Small-Cell Lung
Sponsors & Collaborators
- lead INDUSTRY
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-06-11
- Primary Completion
- 2024-10-27
- Completion
- 2024-10-27
Countries
- South Korea
Study Locations
More Related Trials
-
Efficacy and Safety of 80mg Osimertinib in Patients With Non-small Cell Lung Cancer(NSCLC)
NCT04563871 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy of Osimertinib in Patients With EGFR-sensitive Mutated Non-small Cell Lung Cancer Progression After Receiving Adjuvant Targeted Therapy Following Radical Surgery
NCT06530719 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effect of Osimertinib in Ethnic Chinese With EGFR and T790M Mutated NSCLC
NCT03133234 ·Status: COMPLETED
-
Lazertinib Real-world Observational Study of in Pre-treated EGFR T790M Mutant With Advanced Non-small Cell Lung Cancer
NCT05377788 ·Status: UNKNOWN
-
Osimertinib Study in Indian Patients
NCT03853551 ·Status: COMPLETED ·Phase: PHASE4
-
Neoadjuvant Targeted Therapy in Patients With Resectable EGFR-mutated Lung Squamous Cell Carcinoma
NCT06383728 ·Status: RECRUITING ·Phase: PHASE2
-
Osimertinib In EGFR Mutant Lung Cancer
NCT03586453 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Osimertinib to Suppress the Progression of Remaining GGN for EGFR Mutation-positive Stage IB-IIIA Lung Adenocarcinoma
NCT05528458 ·Status: RECRUITING ·Phase: PHASE2
-
Osimertinib (AZD9291) in First-line Locally Advanced or Metastatic NSCLC Patients With EGFR and EGFR T790M
NCT02841579 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess the Effect of Osimertinib (TAGRISSO™ ) on Blood Levels of Fexofenadine in Patients With EGFRm+ NSCLC
NCT02908750 ·Status: COMPLETED ·Phase: PHASE1
-
A Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Neoadjuvant Osimertinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harbouring EGFR Mutations
NCT04816838 ·Status: RECRUITING ·Phase: NA
-
Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm
NCT05546866 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC
NCT07058519 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase Ib/II Clinical Study of GH21 Capsules Combined With Osimertinib Mesylate Tablets in Patients With NSCLC
NCT06306456 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Osimertinib for Advanced EGFR-positive NSCLC Patients
NCT05037331 ·Status: RECRUITING
-
A Molecular Profiling Study of Patients With EGFR Mutation-positive Locally Advanced or Metastatic NSCLC Treated With Osimertinib
NCT03239340 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Osimertinib for HK Chinese With Metastatic T790M Mutated NSCLC-real World Setting.
NCT03219970 ·Status: COMPLETED
-
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
NCT05120349 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC
NCT05215951 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 2 Study of Osimertinib and S-1 in Treatment Resistant EGFR Mutant NSCLC
NCT05773092 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study
NCT07295821 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations
NCT05801029 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Osimertinib Therapy After Resection in High-risk Stage I EGFRm NSCLC (OSTAR)
NCT05686434 ·Status: RECRUITING ·Phase: PHASE2
-
First-line Treatment With Osimertinib in EGFR-mutated Non-small Cell Lung Cancer
NCT03804580 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Osimertinib in First and Second Line Treatment of NSCLC Harboring EGFR Mutations From Circulating Tumor DNA
NCT02769286 ·Status: COMPLETED ·Phase: PHASE2