Erythropoietin And/Or Iron Sucrose For Perioperative Anemia Management In Hip and Knee Arthroplasty
NCT03917394 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 780
Last updated 2019-04-25
Summary
Perioperative anemia is very common in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA). This study retrospectively analyzes the use of rHuEPO and iron sucrose in patients undergoing total hip and knee arthroplasty in order to observe the short-term efficacy and safety of rHuEPO and iron sucrose.
Conditions
- Anemia, Iron Deficiency
Interventions
- DRUG
-
rHuEPO
rHuEPO was administrated daily with 10000 IU or 20000 IU
- DRUG
-
Iron sucrose
Iron sucrose was administrated daily with 100mg or 200mg
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Principal Investigators
-
Wei Wang, PhD · Peking Union Medical College Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-04-24
- Primary Completion
- 2019-05-30
- Completion
- 2019-09-30
Countries
- China
Study Locations
More Related Trials
-
A Study to Evaluate the Safety of Epoetin Alfa and Its Effectiveness in Facilitating the Presurgical Collection of Blood From Anemic Patients for Possible Self-transfusion During and After Scheduled Joint Surgery.
NCT00270062 ·Status: COMPLETED ·Phase: PHASE3
-
The Benefits of a Preoperative Anemia Management Program
NCT01888003 ·Status: TERMINATED ·Phase: NA
-
A Study to Determine the Safety of Epoetin Alfa and Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients After Major Orthopedic Surgery.
NCT00270036 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Determine an Effective Dose of Epoetin Alfa to Decrease the Number of Units of Blood Required to be Transfused During Hip Replacement Surgery.
NCT00269971 ·Status: WITHDRAWN ·Phase: PHASE3
-
Cross Iron (Comparative Randomized Oral Versus Systemic IRON)
NCT02496377 ·Status: COMPLETED ·Phase: NA
-
A Study to Determine the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Not Anemic and Who Will be Undergoing Orthopedic or Heart and Blood Vessel Surgery
NCT00270075 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS and Advanced ARC Patients With Anemia
NCT00002042 ·Status: COMPLETED ·Phase: NA
-
Intravenous Ferric Carboxymaltose (Ferinject®) With or Without Erythropoietin in Patients Undergoing Orthopaedic Surgery
NCT00706667 ·Status: TERMINATED ·Phase: PHASE4
-
A Study to Evaluate the Effectiveness and Safety of Epoetin Alfa During the Period When One is Donating One's Own Blood Before Surgery.
NCT00270179 ·Status: COMPLETED ·Phase: PHASE3
-
Pre-operative Treatment With Erythropoietin and Iron Supplement in Cardiac Surgery
NCT02210949 ·Status: TERMINATED ·Phase: PHASE4
-
A Study to Determine Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients During the Period of Time Around Major Orthopedic Surgery.
NCT00270088 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia
NCT01114204 ·Status: COMPLETED ·Phase: PHASE3
-
Intravenous (IV) Iron vs. No Iron as the Treatment of Anemia in Cancer Patients Undergoing Chemotherapy and Erythropoietin Therapy
NCT00236951 ·Status: COMPLETED ·Phase: PHASE3
-
The Safety and Effectiveness of r-HuEPO in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Are Anemic
NCT00002303 ·Status: COMPLETED ·Phase: NA
-
Effect of Preoperative Recombinant Human Erythropoietin on Transfusion Risk in Valvular Heart Surgery
NCT00939978 ·Status: COMPLETED ·Phase: NA
-
A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of Subcutaneous Doses of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy
NCT00002073 ·Status: COMPLETED ·Phase: NA
-
The Effect of Intravenous Iron Therapy and Erythropoiesis-stimulation Agent Combination on Renal Transplant Outcomes
NCT05719376 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of Venofer (Iron Sucrose Injection USP) in Patients Receiving Peritoneal Dialysis
NCT00236938 ·Status: COMPLETED ·Phase: PHASE3
-
A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy
NCT00002072 ·Status: COMPLETED ·Phase: NA
-
Erythropoietin and Iron Supplementation for Patients With Chemotherapy-induced Anaemia
NCT02731378 ·Status: UNKNOWN ·Phase: PHASE4
-
Early Administration of Recombinant Erythropoietin (RHEPO) in Transfusion Savings in Trauma Patients
NCT03867071 ·Status: COMPLETED ·Phase: NA
-
A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy
NCT00002071 ·Status: COMPLETED ·Phase: NA
-
Comparison of Oral Iron With IV Iron in Patients With Anemia of Chronic Renal Failure Not on Dialysis
NCT00236964 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetic of Intravenous Iron Sucrose in Adolescents on Hemodialysis or Peritoneal Dialysis Receiving Epoetin
NCT00239616 ·Status: COMPLETED ·Phase: PHASE2
-
Erythropoietin to Improve Critical Care Patient Outcomes
NCT05080049 ·Status: UNKNOWN ·Phase: PHASE3