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Intralesional Steroid Injection Versus Voice Therapy in Management of Vocal Nodules

NCT03914092 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-01-16

No results posted yet for this study

Summary

Vocal nodules represent 16 % of benign vocal fold lesions.They are caused by chronic voice abuse or misuse and often occur in children and adult females. The resultant dysphonia leads to personal, social and occupational problems.

The first line of treatment is voice rest and voice therapy. The Accent method is a holistic technique for behavior readjustment voice therapy which targets various voice parameters as loudness, pitch and timbre. However, voice rest and voice therapy are sometimes difficult to be carried out in patients with voice-related occupations. So, complete resolution may not be possible in all patients. When voice therapy is inefficient, resection is performed by laryngeal microsurgery under general anesthesia. However, the role of surgery is much restricted.

Conditions

  • Vocal Nodules in Adults

Interventions

DRUG

triamcinolone acetonide injection

0.1- 0.3 mm percutaneous intralesional injection

BEHAVIORAL

Smith Accent method of voice therapy

regular sessions of smith accent voice therapy (about 24 sessions, twice session / week) for 3 months

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Nada A Kamel, M.Sc. · Assiut University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-29
Primary Completion
2022-08-15
Completion
2023-08-28

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03914092 on ClinicalTrials.gov