Impact of eHealth Monitoring on Overall Survival in Patients With Metastatic NSCLC / Extensive-stage SCLC / Advanced TNBC Under First-line Treatment With Atezolizumab Plus Chemotherapy
NCT03911219 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 154
Last updated 2021-10-05
Summary
The current study is aimed to test the benefit of a web-based application tool in NSCLC, SCLC and TNBC patients during the recently approved first-line treatment strategy with atezolizumab in combination with chemotherapy.
Conditions
- Stage IV Non-small Cell Lung Cancer
- Extensive-stage Small Cell Lung Cancer
- Advanced (Locally Advanced and Inoperable or Metastatic), PD-L1 IC-positive TNBC
Interventions
- OTHER
-
eHealth system support for symptom management via CANKADO
Regular use of eHealth support system CANKADO by the patient: symptom self-reporting triggering alerts to the patient; in addition to standard of care symptom management.
Sponsors & Collaborators
-
Roche Pharma AG
collaborator INDUSTRY -
iOMEDICO AG
lead INDUSTRY
Principal Investigators
-
Manfred Welslau, Dr. · MVZ am Klinikum Aschaffenburg
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-07-10
- Primary Completion
- 2021-07-01
- Completion
- 2021-07-01
Countries
- Germany
Study Locations
More Related Trials
-
Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer
NCT04622228 ·Status: COMPLETED ·Phase: PHASE2
-
Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma
NCT05689671 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT03735121 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
NCT03285763 ·Status: COMPLETED ·Phase: PHASE4
-
Combined Atezolizumab and Chemotherapy (Carboplatin Plus Etoposide) in Neoadjuvant Treating Limited-Stage Small Cell Lung Cancer Patients
NCT04696939 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy
NCT02008227 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tobemstomig Plus Platinum-Based Chemotherapy vs Pembrolizumab Plus Platinum-Based Chemotherapy in Participants With Previously Untreated Non-Small Cell Lung Cancer
NCT05775289 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Emulation of the KEYNOTE-189 Trial Using Electronic Health Records
NCT05908799 ·Status: COMPLETED
-
A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung
NCT05470595 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Immunotherapy as Second-line in Patient With Small Cell Lung Cancer
NCT03059667 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]
NCT02486718 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Safety and Efficacy Study of Pemetrexed + Platinum Chemotherapy + Pembrolizumab (MK-3475) With or Without Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-7902-006/E7080-G000-315/LEAP-006)
NCT03829319 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Atezolizumab in Advanced Non-oncogene-addicted NSCLC With PD-L1 ≥50%, Including Longitudinal c-FLIP Assessment in Monocytic MDSCs.
NCT07051928 ·Status: NOT_YET_RECRUITING
-
A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer
NCT04832854 ·Status: TERMINATED ·Phase: PHASE2
-
Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
NCT05800587 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Investigate Efficacy and Safety of Ceralasertib Plus Durvalumab in Participants Aged ≥ 18 Years With Advanced or Metastatic Non-small Cell Lung Cancer Whose Disease Progressed on or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy
NCT05941897 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
NCT04765059 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Atezolizumab Combined With Chemotherapy in Extensive Stage SCLC
NCT04920981 ·Status: COMPLETED
-
A Study to Evaluate Participant and Healthcare Professional Reported Preference for Subcutaneous Atezolizumab Compared With Intravenous Atezolizumab Formulation in Participants With Non-Small Cell Lung Cancer
NCT05171777 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer
NCT04619797 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study Evaluating the Efficacy and Safety of Adjuvant Platinum-Doublet Chemotherapy, With or Without Atezolizumab, in Patients Who Are ctDNA Positive After Complete Surgical Resection of Stage IB to Select IIIB Non-Small Cell Lung Cancer
NCT04611776 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]
NCT02409342 ·Status: COMPLETED ·Phase: PHASE3
-
Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer
NCT03540420 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower111)
NCT02409355 ·Status: TERMINATED ·Phase: PHASE3
-
Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)
NCT04367311 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2