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Multi-centre Acute Severe Ulcerative Colitis Prospective Cohort Study (Elevate ASUC)

NCT03907631 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 189

Last updated 2026-02-17

No results posted yet for this study

Summary

Up to one third of patients with Ulcerative Colitis (UC) will require hospitalisation for severe disease (ASUC - Acute Severe Ulcerative Colitis), often within the first 12 months of diagnosis. 30-40% of people admitted to hospital with ASUC will require colectomy during the emergency admission. Investigators will develop a multi-centre prospective inception cohort of patients with ASUC with homogeneously collected detailed longitudinal clinical, endoscopic and laboratory data.

Conditions

  • Severe Ulcerative Colitis

Interventions

OTHER

Standard of care

care decisions driven by local physicians; this is an observational cohort

Sponsors & Collaborators

  • Hull University Teaching Hospitals NHS Trust

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-10-18
Primary Completion
2024-01-31
Completion
2026-08-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03907631 on ClinicalTrials.gov