Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System
NCT03889093 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2025-03-24
Summary
The goal of this study is to understand the immunologic effects radioembolization has on the immune system. This will be done by evaluating the changes on biopsy, peripheral blood monocytes, and cytokines.
Conditions
- Hepatocellular Carcinoma
- Secondary Malignant Neoplasm of Liver
Interventions
- OTHER
-
Yttrium-90
This is to evaluate the immunologic effects of yttrium 90.
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Shamar J Young, Young · University of Minnesota
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 22 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-08-09
- Primary Completion
- 2022-02-24
- Completion
- 2022-02-24
Countries
- United States
Study Locations
More Related Trials
-
Optimizing Y90 Therapy for Radiation Lobectomy
NCT04390724 ·Status: RECRUITING
-
Individualized Stereotactic Body Radiotherapy of Liver Metastases
NCT01239381 ·Status: COMPLETED ·Phase: NA
-
Promoting Immunotherapy Efficacy With Low-Dose Liver RT
NCT07225036 ·Status: RECRUITING ·Phase: NA
-
Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy.
NCT04518748 ·Status: RECRUITING ·Phase: PHASE1
-
Stereotactic Radiation Therapy in Treating Patients With Liver Metastases
NCT00938457 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Pilot Study of Trans Arterial Chemoembolization (TACE), Followed by Stereotactic Radiation Therapy (SBRT) for Patients With Hepatocellular Carcinoma
NCT01247298 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer
NCT03812289 ·Status: TERMINATED ·Phase: NA
-
Detection of Circulating Biomarkers of Immunogenic Cell Death
NCT02921854 ·Status: COMPLETED ·Phase: NA
-
Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant
NCT06725121 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction
NCT06362395 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Metastatic Tumors to the Liver
NCT01030757 ·Status: TERMINATED ·Phase: PHASE2
-
MR-Guided Laser Ablation of Hepatic Tumors
NCT01630239 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response
NCT02439008 ·Status: TERMINATED ·Phase: NA
-
Cryoablation in Combination (or Not) With Pembrolizumab and Pemetrexed-carboplatin in 1st-line Treatment for Patients With Metastatic Lung Adenocarcinoma
NCT04339218 ·Status: RECRUITING ·Phase: PHASE3
-
Immunotherapy SBRT Sensitization of the Programmed Death-1 (PD-1) Effect
NCT03825510 ·Status: COMPLETED ·Phase: PHASE2
-
Y-90 Versus SBRT for Inoperable HCC
NCT05157451 ·Status: WITHDRAWN ·Phase: PHASE2
-
LITT and Pembrolizumab in Recurrent Brain Metastasis
NCT04187872 ·Status: TERMINATED ·Phase: PHASE1
-
Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer and Cholangiocarcinoma
NCT00976898 ·Status: COMPLETED ·Phase: NA
-
Stereotactic Radiosurgery for Patients With Hepatic Metastases.
NCT00547677 ·Status: COMPLETED ·Phase: PHASE1
-
A Multi-mode Thermophysical Immunotherapy Study for Breast Cancer Liver Metastases
NCT06567353 ·Status: RECRUITING ·Phase: NA
-
Liver Function Investigation With SPECT
NCT02967848 ·Status: ACTIVE_NOT_RECRUITING
-
Stereotactic Radiosurgery Dose Escalation for Brain Metastases
NCT02390518 ·Status: RECRUITING ·Phase: PHASE1
-
Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Liver Tumors
NCT00691691 ·Status: UNKNOWN ·Phase: PHASE2
-
Selective Intra-arterial Injection of PRRT in Neuroendocrine Tumor Patients With Liver Metastases
NCT03724409 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC
NCT02463994 ·Status: COMPLETED ·Phase: EARLY_PHASE1