Trial Outcomes & Findings for Parkinson's Disease Inpatient Clinical Knowledge and Management (NCT NCT03888287)

NCT ID: NCT03888287

Last Updated: 2023-04-18

Results Overview

Clinician's Parkinson's Disease Knowledge Assessment Survey scores before and after the Parkinson's Disease Inpatient Clinical Knowledge and Management Program. A 20-question survey was administered to PD clinicians for a group measurement of PD knowledge. Scores ranged from 0 - 100% and reflected the percentage of clinicians who correctly answered the question. If 70% or more clinicians correctly answered the question, the group was considered knowledgeable on that topic; if \<70% of clinicians responded incorrectly, they were considered not knowledgeable on the information that the question assessed. Survey questions addressed three PD areas: 1) medication/treatment, 2) symptoms/diagnosis, and 3) epidemiology/pathophysiology.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

477 participants

Primary outcome timeframe

6 months

Results posted on

2023-04-18

Participant Flow

Participant milestones

Participant milestones
Measure
Retrospective Phase
Patients with Parkinson's disease before completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program.
Prospective Phase-Watch Rx System
Patients after completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program who are also assigned to a WatchRx system
Retrospective Phase - Clinicians
Clinicians, including physician's assistants, advanced practice nurses, staff nurses, nurse educators, case managers, dietitians pharmacists physical therapists, and occupational therapists before completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program.
Prospective Phase - Clinicians
Clinicians, including physician's assistants, advanced practice nurses, staff nurses, nurse educators, case managers, dietitians pharmacists physical therapists and occupational therapists after completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program.
Overall Study
STARTED
131
0
266
80
Overall Study
COMPLETED
131
0
266
80
Overall Study
NOT COMPLETED
0
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Information/demographics of clinicians was never collected.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Retrospective Phase
n=131 Participants
Patients with Parkinson's disease before completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program.
Prospective Phase-Watch Rx System
Patients after completion of the Parkinson's Disease Inpatient Clinical Knowledge and Management Program who are also assigned to a WatchRx system
Total
n=131 Participants
Total of all reporting groups
Age, Customized
76 years
STANDARD_DEVIATION 14.4 • n=99 Participants
76 years
STANDARD_DEVIATION 14.4 • n=206 Participants
Sex: Female, Male
Female
54 Participants
n=99 Participants • Information/demographics of clinicians was never collected.
0 Participants
n=107 Participants • Information/demographics of clinicians was never collected.
54 Participants
n=206 Participants • Information/demographics of clinicians was never collected.
Sex: Female, Male
Male
77 Participants
n=99 Participants • Information/demographics of clinicians was never collected.
0 Participants
n=107 Participants • Information/demographics of clinicians was never collected.
77 Participants
n=206 Participants • Information/demographics of clinicians was never collected.
Ethnicity (NIH/OMB)
Hispanic or Latino
23 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
23 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Ethnicity (NIH/OMB)
Not Hispanic or Latino
107 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
107 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
1 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
0 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
Asian
4 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
4 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
0 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
Black or African American
4 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
4 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
White
106 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
106 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
More than one race
0 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
0 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Race (NIH/OMB)
Unknown or Not Reported
17 Participants
n=99 Participants • Demographic data was never collected on clinicians.
0 Participants
n=107 Participants • Demographic data was never collected on clinicians.
17 Participants
n=206 Participants • Demographic data was never collected on clinicians.
Region of Enrollment
United States
131 participants
n=99 Participants
477 participants
n=206 Participants

PRIMARY outcome

Timeframe: 6 months

Population: Number of clinicians that completed the pre and post intervention surveys

Clinician's Parkinson's Disease Knowledge Assessment Survey scores before and after the Parkinson's Disease Inpatient Clinical Knowledge and Management Program. A 20-question survey was administered to PD clinicians for a group measurement of PD knowledge. Scores ranged from 0 - 100% and reflected the percentage of clinicians who correctly answered the question. If 70% or more clinicians correctly answered the question, the group was considered knowledgeable on that topic; if \<70% of clinicians responded incorrectly, they were considered not knowledgeable on the information that the question assessed. Survey questions addressed three PD areas: 1) medication/treatment, 2) symptoms/diagnosis, and 3) epidemiology/pathophysiology.

Outcome measures

Outcome measures
Measure
Clinicians' Knowledge Before Educational Intervention
n=266 Participants
Average clinician's participant PD score before educational intervention
Clinicians' Knowledge After Educational Intervention
n=80 Participants
Average clinician's participant PD score after educational intervention
Clinician's Parkinson's Disease Knowledge Assessment Survey Scores
68.50 average knowledge score
Interval 0.0 to 100.0
78.75 average knowledge score
Interval 0.0 to 100.0

SECONDARY outcome

Timeframe: within 15 minutes post PD medication administration time

Population: No patients were enrolled in the study after clinician education

The number of Parkinson's Disease (PD) medications administered within the 15-minute timeframe at baseline

Outcome measures

Outcome measures
Measure
Clinicians' Knowledge Before Educational Intervention
n=2454 Number of scheduled PD medications
Average clinician's participant PD score before educational intervention
Clinicians' Knowledge After Educational Intervention
Average clinician's participant PD score after educational intervention
Number of PD Medications Administered on Time (15 Minute Window)
678 number of PD meds administered in 15 min

SECONDARY outcome

Timeframe: 6 months

Population: No patients were enrolled in the study after clinician education

Measure the number of patients who were adminstered contraindicated medications

Outcome measures

Outcome measures
Measure
Clinicians' Knowledge Before Educational Intervention
n=131 Participants
Average clinician's participant PD score before educational intervention
Clinicians' Knowledge After Educational Intervention
Average clinician's participant PD score after educational intervention
Number of Patients With Contraindicated Medications Administered.
21 Participants

SECONDARY outcome

Timeframe: 6 Months

Population: Patients were not enrolled after clinical education

The number of falls, number of falls with injury, and number of patients with positive Confusion Assessment Method (CAM)/Mini-Cog scores) in hospitalized patients. Mini-cog is performed on all admitted patients 65 years and older and is a quick screening for "cognitive vital sign" and early dementia detection. The scale classifies patients as being positive or negative for dementia. The Confusion Assessment Method (CAM) is performed on all adult admissions at the time of admission with reporting 1) every shift if the first test is positive, or 2) daily if the first test is negative. It improves the detection and recognition of delirium accurately and quickly in clinical and research settings. CAM is documentation of observed patient behavior during brief, structured interviews according to classification of positive or negative for dementia. There are no numerical (minimum or maximum) values assigned.

Outcome measures

Outcome measures
Measure
Clinicians' Knowledge Before Educational Intervention
n=93 Participants
Average clinician's participant PD score before educational intervention
Clinicians' Knowledge After Educational Intervention
Average clinician's participant PD score after educational intervention
Number Patients With Falls, Falls With Injury, Positive CAM/Mini-cog
Number of falls
1 Participants
Number Patients With Falls, Falls With Injury, Positive CAM/Mini-cog
Number of falls with injury
0 Participants
Number Patients With Falls, Falls With Injury, Positive CAM/Mini-cog
Number of patients with positive CAM scores
47 Participants
Number Patients With Falls, Falls With Injury, Positive CAM/Mini-cog
Number of patients with abnormal mini-cog scores
45 Participants

SECONDARY outcome

Timeframe: 6 months

Population: Patients were not enrolled after clinical education

Average length of stay in hospitalized Parkinson's Disease patients

Outcome measures

Outcome measures
Measure
Clinicians' Knowledge Before Educational Intervention
n=131 Participants
Average clinician's participant PD score before educational intervention
Clinicians' Knowledge After Educational Intervention
Average clinician's participant PD score after educational intervention
Length of Stay in Hospitalized Parkinson's Disease Patients.
6.1 days
Standard Deviation 6.6

SECONDARY outcome

Timeframe: 15 minutes post assigned medication administration time.

Population: No patients were enrolled for the WatchRX system

Track the difference that the WatchRx system has on scheduled PD medication administration time versus actual PD medication administration time

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 Months

Population: No patients were enrolled in the WatchRX system

The number of contraindicated medications administered to Parkinson's disease patients after using the WatchRX system

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: No patient enrollment into the WatchRX system

The number of falls, number of falls with injury, number of positive CAM scores, and number of positive Mini-Cog scores after using the WatchRX system.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months

Population: No patients were enrolled into the WatchRX system

Parkinson's disease patients' length of stay after using the WatchRx system

Outcome measures

Outcome data not reported

Adverse Events

Retrospective Phase - Watch Rx System

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Prospective Phase - Watch Rx System

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Retrospective Phase - Clinicians

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Prospective Phase - Clinicians

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Hooman Azmi, MD

Hackensack Meridian Health

Phone: 201-342-2550

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place