Anlotinib Hydrochloride Combined With Liposomal Doxorubicin in the Treatment of Locally Advanced or Metastatic Soft Tissue Sarcoma
NCT03880695 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2019-03-21
Summary
The investigators explored the activity of anlotinib combined with Liposomal Doxorubicin in patients with Locally Advanced or Metastatic Soft Tissue Sarcoma
Conditions
- Sarcoma
Interventions
- DRUG
-
Anlotinib+ Liposomal Doxorubicin
Anlotinib : 12 mg, qd, po day 8-21 every 3 weeks Liposomal Doxorubicin: 50 mg/m2, day 1 every 3 weeks
Sponsors & Collaborators
-
Peking University Shougang Hospital
collaborator OTHER -
Peking University Cancer Hospital & Institute
collaborator OTHER -
Tianjin Medical University Cancer Institute and Hospital
collaborator OTHER -
The First Hospital of Jilin University
collaborator OTHER -
Hunan Cancer Hospital
collaborator OTHER -
Ruijin Hospital
collaborator OTHER -
Liaoning Cancer Hospital & Institute
collaborator OTHER -
Peking University People's Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 14 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-31
- Primary Completion
- 2021-04-30
- Completion
- 2021-05-31
Countries
- China
Study Locations
More Related Trials
-
Anlotinib Combined With Chemotherapy for the Treatment of HER2 Negative Advanced Breast Cancer
NCT05334147 ·Status: UNKNOWN
-
A Phase Ⅱ Study of Anlotinib Combined With Tislelizumab and AT in the Neoadjuvant Treatment of Triple-negative Breast Cancer
NCT04914390 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Olaratumab (LY3012207) in Participants With Soft Tissue Sarcoma
NCT02783599 ·Status: COMPLETED ·Phase: PHASE1
-
Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma
NCT05711615 ·Status: RECRUITING ·Phase: PHASE1
-
A Clinical Trial to Evaluate TQB2858 Injection Combined With Anlotinib Hydrochloride Capsule in the Treatment of Recurrent or Metastatic Advanced Endometrial Carcinoma
NCT05121363 ·Status: UNKNOWN ·Phase: PHASE2
-
Anlotinib-based Combination Therapy in Patients with Hormone Receptor-positive(HR+) Metastatic Breast Cancer(MBC) .
NCT06734533 ·Status: RECRUITING
-
Safety, Tolerability, and Pharmacokinetics of Proxalutamide Therapy in Women With Metastatic Breast Cancer
NCT04103853 ·Status: COMPLETED ·Phase: PHASE1
-
Pelareorep and Paclitaxel Injection in Chinese Patients With Advanced or Metastatic Breast Cancer
NCT05519059 ·Status: COMPLETED ·Phase: PHASE1
-
An Exploratory Clinical Study of Dalpiciclib an&Amp;#39;d Letrozole Combined With Anlotinib Neoadjuvant Therapy in Stage II-III Postmenopausal HR+/HER2- Early Breast Cancer
NCT06605690 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Paclitaxel for Injection (Albumin Bound) in Subjects With Triple Negative Breast Cancer (TNBC)
NCT04405505 ·Status: UNKNOWN ·Phase: PHASE3
-
Eribulin Combined With Anlotinib in Metastatic HER2 Negative Breast Cancer
NCT04624711 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of LY2875358 in Japanese Participants With Advanced Cancer
NCT01602289 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Eribullin or Eribulin Combined With Anlotinib in Metastatic Breast Cancer
NCT05206656 ·Status: COMPLETED ·Phase: PHASE2
-
Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies
NCT02807844 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Molecular Alterations Associated With Resistance to Endocrine Therapy and Impacting Treatment With mTOR Inhibitor
NCT02444390 ·Status: COMPLETED ·Phase: NA
-
A Trial of LBL-024 Monotherapy or Combination Drug in Patients With Triple Negative Breast Cancer
NCT07281976 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of Mitoxantrone Hydrochloride Liposome Injection in Patients With Advanced HER2 Negative Breast Cancer
NCT04927481 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Safety of DEB-BACE With Sequential Arotinib and Tirelizumab in the Treatment of Advanced NSCLC
NCT05380271 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Trial of HRS-1358 Tablets in Metastatic or Local Advanced Breast Cancer
NCT05628870 ·Status: RECRUITING ·Phase: PHASE1
-
Anlotinib With Trastuzumab Deruxtecan for Previously Treated HER2-Low Advanced Breast Cancer
NCT06331169 ·Status: RECRUITING ·Phase: PHASE1
-
Albumin-bound Paclitaxel、Dalpiciclib and AI in ER-Low (1%-10%) HER2-ABC
NCT06711094 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy
NCT05979220 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Real-world Efficacy and Safety Study of Amlotinib for HER2-negative Advanced Breast Cancer
NCT06340165 ·Status: RECRUITING
-
Lapatinib Combined With Paclitaxel For Patients With First-Line ErbB2-Amplified Metastatic Breast Cancer
NCT00356811 ·Status: COMPLETED ·Phase: PHASE2
-
ErbB2 Positive Metastatic Breast Cancer
NCT01658358 ·Status: TERMINATED ·Phase: PHASE1/PHASE2