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Multicenter, Prospective Study for Urinary Exosomal Biomarkers of Kidney Allograft Tubulointerstitial Fibrosis

NCT03870542 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2019-09-24

No results posted yet for this study

Summary

The investigators aim to identify urinary exosomal biomarkers that represent the extent of graft fibrosis from deceased donor kidney transplantation. Urinary samples will be collected from deceased kidney donors at the time of procurement and zero-day kidney graft biopsy will be performed at the time of transplant. The association between urinary exosomes and the degree of graft fibrosis will be analyzed to identify biomarkers that represent fibrosis. The correlation between these biomarkers and graft long term outcomes will be investigated.

Conditions

  • Renal Fibrosis
  • Kidney Transplant Failure

Interventions

PROCEDURE

kidney transplantation

Kidney transplant for end-stage renal disease from deceased kidney donors

Sponsors & Collaborators

  • Korea University Anam Hospital

    collaborator OTHER

  • Inje University

    collaborator OTHER

  • Ulsan University Hospital

    collaborator OTHER

  • Hallym University Medical Center

    collaborator OTHER

  • Asan Medical Center

    lead OTHER

Principal Investigators

  • Sung Shin, MD, PhD · Asan Medical Center

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-05-11
Primary Completion
2022-04-30
Completion
2022-04-30

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03870542 on ClinicalTrials.gov